264841

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1457575..1458491 Replicon chromosome
Accession NZ_CP111073
Organism Bacillus inaquosorum strain BSXE-2102

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag OP701_RS07170 Protein ID WP_060398450.1
Coordinates 1457745..1458491 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID G4NV07
Locus tag OP701_RS07165 Protein ID WP_003239095.1
Coordinates 1457575..1457745 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP701_RS07125 (OP701_07125) 1452655..1454424 + 1770 WP_248596976.1 terminase -
OP701_RS07130 (OP701_07130) 1454436..1454765 + 330 WP_060398446.1 XkdW family protein -
OP701_RS07135 (OP701_07135) 1454762..1454926 + 165 WP_019258164.1 XkdX family protein -
OP701_RS07140 (OP701_07140) 1454973..1455812 + 840 WP_060398447.1 hypothetical protein -
OP701_RS07145 (OP701_07145) 1455865..1456134 + 270 WP_060398448.1 hemolysin XhlA family protein -
OP701_RS07150 (OP701_07150) 1456147..1456410 + 264 WP_003239099.1 phage holin -
OP701_RS07155 (OP701_07155) 1456423..1457316 + 894 WP_060398449.1 N-acetylmuramoyl-L-alanine amidase -
OP701_RS07160 (OP701_07160) 1457353..1457490 - 138 WP_119913750.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
OP701_RS07165 (OP701_07165) 1457575..1457745 - 171 WP_003239095.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
OP701_RS07170 (OP701_07170) 1457745..1458491 - 747 WP_060398450.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
OP701_RS07175 (OP701_07175) 1458601..1459602 - 1002 WP_003239093.1 inorganic phosphate transporter -
OP701_RS07180 (OP701_07180) 1459615..1460232 - 618 WP_003218470.1 DUF47 domain-containing protein -
OP701_RS07185 (OP701_07185) 1460508..1461824 - 1317 WP_060398451.1 serine/threonine exchanger -
OP701_RS07190 (OP701_07190) 1462210..1463160 + 951 WP_060398452.1 ring-cleaving dioxygenase -
OP701_RS07195 (OP701_07195) 1463261..1463406 + 146 Protein_1354 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29097.57 Da        Isoelectric Point: 4.6191

>T264841 WP_060398450.1 NZ_CP111073:c1458491-1457745 [Bacillus inaquosorum]
MLLFFQIMVWCVMAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPSSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQNRLDRKDVYYDQYGKMVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6555.59 Da        Isoelectric Point: 10.8401

>AT264841 WP_003239095.1 NZ_CP111073:c1457745-1457575 [Bacillus inaquosorum]
MERAFQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G4NV07

References