264839

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1210206..1211123 Replicon chromosome
Accession NZ_CP111072
Organism Bacillus velezensis strain YFI-E109

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag OQE53_RS06350 Protein ID WP_007407256.1
Coordinates 1210377..1211123 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag OQE53_RS06345 Protein ID WP_003154807.1
Coordinates 1210206..1210376 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQE53_RS06305 1205439..1207061 + 1623 WP_032874601.1 pyocin knob domain-containing protein -
OQE53_RS06310 1207074..1207445 + 372 WP_032874603.1 XkdW family protein -
OQE53_RS06315 1207450..1207647 + 198 WP_032874605.1 XkdX family protein -
OQE53_RS06320 1207704..1208465 + 762 WP_032874607.1 hypothetical protein -
OQE53_RS06325 1208517..1208780 + 264 WP_003154815.1 hemolysin XhlA family protein -
OQE53_RS06330 1208794..1209057 + 264 WP_003154813.1 phage holin -
OQE53_RS06335 1209071..1209949 + 879 WP_032874609.1 N-acetylmuramoyl-L-alanine amidase -
OQE53_RS06340 1209984..1210109 - 126 WP_003154809.1 hypothetical protein -
OQE53_RS06345 1210206..1210376 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OQE53_RS06350 1210377..1211123 - 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OQE53_RS06355 1211228..1212226 - 999 WP_032874611.1 inorganic phosphate transporter -
OQE53_RS06360 1212239..1212856 - 618 WP_032874614.1 DUF47 domain-containing protein -
OQE53_RS06365 1213142..1214458 - 1317 WP_032874616.1 amino acid permease -
OQE53_RS06370 1214780..1215730 + 951 WP_032874618.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T264839 WP_007407256.1 NZ_CP111072:c1211123-1210377 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT264839 WP_003154807.1 NZ_CP111072:c1210376-1210206 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References