Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 170690..171240 Replicon plasmid pPALA54
Accession NZ_CP111033
Organism Pseudomonas aeruginosa strain PALA54

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PALA54_RS32945 Protein ID WP_034061810.1
Coordinates 170690..170968 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PALA54_RS32950 Protein ID WP_034061812.1
Coordinates 170968..171240 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PALA54_RS32925 (PALA54_06501) 167233..169083 + 1851 WP_049267175.1 tyrosine-type recombinase/integrase -
PALA54_RS32930 169080..169592 + 513 WP_044305333.1 hypothetical protein -
PALA54_RS32935 (PALA54_06502) 169605..169847 - 243 WP_034061808.1 hypothetical protein -
PALA54_RS32940 (PALA54_06503) 169861..170688 - 828 WP_034061809.1 hypothetical protein -
PALA54_RS32945 (PALA54_06504) 170690..170968 - 279 WP_034061810.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PALA54_RS32950 (PALA54_06505) 170968..171240 - 273 WP_034061812.1 ribbon-helix-helix domain-containing protein Antitoxin
PALA54_RS32955 171434..171874 - 441 WP_128734628.1 hypothetical protein -
PALA54_RS32960 (PALA54_06506) 171884..172630 - 747 WP_034061813.1 DUF2807 domain-containing protein -
PALA54_RS32965 (PALA54_06507) 172772..173920 - 1149 WP_034061814.1 site-specific integrase -
PALA54_RS32970 (PALA54_06508) 174082..174894 - 813 Protein_211 site-specific integrase -
PALA54_RS32975 (PALA54_06509) 174860..175126 - 267 WP_034061816.1 helix-turn-helix transcriptional regulator -
PALA54_RS32980 (PALA54_06510) 175264..175929 - 666 WP_034061819.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..177374 177374


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10844.46 Da        Isoelectric Point: 8.5041

>T264830 WP_034061810.1 NZ_CP111033:c170968-170690 [Pseudomonas aeruginosa]
MELKWTSKALSDLARLYEFLAAVNRPAAARTVQQLTVTPTTLLTNPRIGERLEEFEPRDVRRILVGHYEMRYEIAADSTI
YLLRLWHTREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10054.25 Da        Isoelectric Point: 4.8616

>AT264830 WP_034061812.1 NZ_CP111033:c171240-170968 [Pseudomonas aeruginosa]
MAATAKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPH

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References