264803

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 2248431..2248953 Replicon chromosome
Accession NZ_CP111029
Organism Salmonella sp. 2018103

Toxin (Protein)


Gene name stbE Uniprot ID A0A5J1ICX1
Locus tag OLG56_RS10925 Protein ID WP_000221344.1
Coordinates 2248431..2248715 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID V1H457
Locus tag OLG56_RS10930 Protein ID WP_000885424.1
Coordinates 2248705..2248953 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLG56_RS10900 (2243435) 2243435..2244676 - 1242 WP_001095734.1 MFS transporter -
OLG56_RS10905 (2244666) 2244666..2246174 - 1509 WP_053258905.1 FAD-dependent oxidoreductase -
OLG56_RS10910 (2246219) 2246219..2246707 + 489 WP_001293634.1 MarR family winged helix-turn-helix transcriptional regulator -
OLG56_RS10915 (2246900) 2246900..2247979 + 1080 WP_079900464.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
OLG56_RS10920 (2248031) 2248031..2248312 - 282 Protein_2134 RidA family protein -
OLG56_RS10925 (2248431) 2248431..2248715 - 285 WP_000221344.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OLG56_RS10930 (2248705) 2248705..2248953 - 249 WP_000885424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OLG56_RS10935 (2249105) 2249105..2249224 + 120 Protein_2137 type II and III secretion system -
OLG56_RS10940 (2249310) 2249310..2249642 + 333 WP_000253078.1 DUF1493 family protein -
OLG56_RS10945 (2249917) 2249917..2250087 - 171 WP_000415762.1 DUF29 family protein -
OLG56_RS10950 (2250499) 2250499..2251407 + 909 WP_001176637.1 LysR family transcriptional regulator -
OLG56_RS10955 (2251581) 2251581..2252561 + 981 WP_000876807.1 nitronate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11015.73 Da        Isoelectric Point: 10.5388

>T264803 WP_000221344.1 NZ_CP111029:c2248715-2248431 [Salmonella sp. 2018103]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKVTQHRS

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.32 Da        Isoelectric Point: 3.9820

>AT264803 WP_000885424.1 NZ_CP111029:c2248953-2248705 [Salmonella sp. 2018103]
MAFQILTTTAASITELKRDPMGTFNAGDGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5J1ICX1

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0WPN5

References