Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 826300..826960 Replicon chromosome
Accession NZ_CP111029
Organism Salmonella sp. 2018103

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I1G658
Locus tag OLG56_RS03975 Protein ID WP_001727955.1
Coordinates 826547..826960 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag OLG56_RS03970 Protein ID WP_000351186.1
Coordinates 826300..826566 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLG56_RS03950 (822229) 822229..823662 - 1434 WP_001230152.1 6-phospho-beta-glucosidase BglA -
OLG56_RS03955 (823820) 823820..824131 + 312 WP_001182972.1 N(4)-acetylcytidine aminohydrolase -
OLG56_RS03960 (824295) 824295..824954 + 660 WP_000250289.1 hemolysin III family protein -
OLG56_RS03965 (825070) 825070..826050 - 981 WP_000874169.1 tRNA-modifying protein YgfZ -
OLG56_RS03970 (826300) 826300..826566 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
OLG56_RS03975 (826547) 826547..826960 + 414 WP_001727955.1 protein YgfX Toxin
OLG56_RS03980 (827013) 827013..827534 - 522 WP_052942704.1 flavodoxin FldB -
OLG56_RS03985 (827647) 827647..828543 + 897 WP_000434300.1 site-specific tyrosine recombinase XerD -
OLG56_RS03990 (828567) 828567..829280 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OLG56_RS03995 (829286) 829286..831019 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16201.18 Da        Isoelectric Point: 10.7537

>T264802 WP_001727955.1 NZ_CP111029:826547-826960 [Salmonella sp. 2018103]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMMLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT264802 WP_000351186.1 NZ_CP111029:826300-826566 [Salmonella sp. 2018103]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I1G658

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References