Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 3886560..3887374 | Replicon | chromosome |
Accession | NZ_CP111008 | ||
Organism | Escherichia coli strain J53-p130 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | ORI87_RS19075 | Protein ID | WP_001054376.1 |
Coordinates | 3886560..3886817 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | ORI87_RS19080 | Protein ID | WP_001309181.1 |
Coordinates | 3886829..3887374 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ORI87_RS19050 (3881848) | 3881848..3882954 | + | 1107 | WP_001309184.1 | N-acetylneuraminate epimerase | - |
ORI87_RS19055 (3883019) | 3883019..3883999 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
ORI87_RS19060 (3884109) | 3884109..3884314 | + | 206 | Protein_3727 | HNH endonuclease | - |
ORI87_RS19065 (3884582) | 3884582..3885822 | - | 1241 | Protein_3728 | helicase YjhR | - |
ORI87_RS19070 (3885938) | 3885938..3886069 | + | 132 | WP_001309182.1 | hypothetical protein | - |
ORI87_RS19075 (3886560) | 3886560..3886817 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
ORI87_RS19080 (3886829) | 3886829..3887374 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
ORI87_RS19085 (3887430) | 3887430..3888176 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
ORI87_RS19090 (3888345) | 3888345..3888563 | + | 219 | Protein_3733 | hypothetical protein | - |
ORI87_RS19095 (3888601) | 3888601..3888717 | + | 117 | Protein_3734 | VOC family protein | - |
ORI87_RS19100 (3888962) | 3888962..3890083 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
ORI87_RS19105 (3890080) | 3890080..3890358 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
ORI87_RS19110 (3890370) | 3890370..3891683 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimB | 3879054..3895598 | 16544 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T264792 WP_001054376.1 NZ_CP111008:3886560-3886817 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT264792 WP_001309181.1 NZ_CP111008:3886829-3887374 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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