Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_XRE
Location 3024801..3025455 Replicon chromosome
Accession NZ_CP110978
Organism Escherichia coli strain XYEH3934

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ORI33_RS14565 Protein ID WP_106408893.1
Coordinates 3024801..3025136 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ORI33_RS14570 Protein ID WP_001280945.1
Coordinates 3025126..3025455 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ORI33_RS14545 (3020754) 3020754..3021380 + 627 WP_001295292.1 glutathione S-transferase GstB -
ORI33_RS14550 (3021377) 3021377..3022492 - 1116 WP_000554946.1 aldose sugar dehydrogenase YliI -
ORI33_RS14555 (3022603) 3022603..3022986 - 384 WP_000497137.1 biofilm formation regulator BssR -
ORI33_RS14560 (3023199) 3023199..3024524 + 1326 WP_000049367.1 30S ribosomal protein S12 methylthiotransferase RimO -
ORI33_RS14565 (3024801) 3024801..3025136 + 336 WP_106408893.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ORI33_RS14570 (3025126) 3025126..3025455 + 330 WP_001280945.1 DNA-binding transcriptional regulator Antitoxin
ORI33_RS14575 (3025525) 3025525..3026853 - 1329 WP_000086877.1 GGDEF domain-containing protein -
ORI33_RS14580 (3026861) 3026861..3029203 - 2343 WP_001400151.1 EAL domain-containing protein -
ORI33_RS14585 (3029381) 3029381..3030292 - 912 WP_001236042.1 glutathione ABC transporter permease GsiD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-94)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12354.14 Da        Isoelectric Point: 6.4754

>T264652 WP_106408893.1 NZ_CP110978:3024801-3025136 [Escherichia coli]
IHDKVLMAAAEEVMQGIWEADLGSGVIKKRLPLQQGKSGGARTIIFFKSANHVFFYDGWSKSGLSSKGTKEIEDDELAAY
KKMANAFLAFSNKQIEDLIETGFLIEVKNER

Download         Length: 336 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11982.08 Da        Isoelectric Point: 10.0101

>AT264652 WP_001280945.1 NZ_CP110978:3025126-3025455 [Escherichia coli]
MSDKLQMMLEDAKELNALGLMSDSEVDAIAVMVKAREVSARIAKVKSMTGEEIKAIRTRYGMSQSVLAHTMGMSKESVSK
WERNEIKPSGPALRILNTLAIKGPEVFAK

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References