Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 327218..327792 Replicon chromosome
Accession NZ_CP110973
Organism Larkinella insperata strain LMG22510

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OQ371_RS01165 Protein ID WP_265991806.1
Coordinates 327218..327475 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OQ371_RS01170 Protein ID WP_265991808.1
Coordinates 327463..327792 (+) Length 110 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ371_RS01155 324028..324528 + 501 WP_265991804.1 hypothetical protein -
OQ371_RS01160 324525..326987 - 2463 WP_265991805.1 TonB-dependent receptor -
OQ371_RS01165 327218..327475 + 258 WP_265991806.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
OQ371_RS01170 327463..327792 + 330 WP_265991808.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
OQ371_RS01175 327805..328554 - 750 WP_265991810.1 acyl-CoA desaturase -
OQ371_RS01180 328740..328907 + 168 WP_265991812.1 cbb3-type cytochrome oxidase assembly protein CcoS -
OQ371_RS01185 328923..331121 + 2199 WP_265991814.1 cytochrome-c oxidase, cbb3-type subunit I -
OQ371_RS01190 331199..331369 + 171 WP_265991816.1 hypothetical protein -
OQ371_RS01195 331382..332224 + 843 WP_265991818.1 cbb3-type cytochrome c oxidase N-terminal domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(7-106)


Sequences


Toxin        


Download         Length: 86 a.a.        Molecular weight: 9441.47 Da        Isoelectric Point: 4.1541

>T264638 WP_265991806.1 NZ_CP110973:327218-327475 [Larkinella insperata]
MVQTIRKFGNSQGILLPRTVLQQAGIEGAVDIEIAEGALILRAVKRHPRDGWEAAFDEAIQSGDQPDGDLFEGTSNQFDQ
TEWTW

Download         Length: 258 bp


Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12211.09 Da        Isoelectric Point: 8.5152

>AT264638 WP_265991808.1 NZ_CP110973:327463-327792 [Larkinella insperata]
MDMVIGRFEVWLVSLDPTQGSEIAKTRPCLVVSPNTINQRLNTVMVSPMTSTQKRYPTRVNCHFAGQDGQVALDQTRSVD
KSRLVKRIGNLDDATCHQVCQVLVAIFTY

Download         Length: 330 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References