Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 3054406..3054767 Replicon chromosome
Accession NZ_CP110921
Organism Methylococcus sp. 16-5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OOT43_RS14525 Protein ID WP_266021285.1
Coordinates 3054406..3054573 (-) Length 56 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OOT43_RS14530 Protein ID WP_266021286.1
Coordinates 3054570..3054767 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOT43_RS14510 (OOT43_14510) 3050759..3052108 + 1350 WP_266021282.1 DNA recombination protein RmuC -
OOT43_RS14515 (OOT43_14515) 3052113..3054023 - 1911 WP_266021283.1 DCC1-like thiol-disulfide oxidoreductase family protein -
OOT43_RS14520 (OOT43_14520) 3054205..3054405 - 201 WP_266021284.1 hypothetical protein -
OOT43_RS14525 (OOT43_14525) 3054406..3054573 - 168 WP_266021285.1 hypothetical protein Toxin
OOT43_RS14530 (OOT43_14530) 3054570..3054767 - 198 WP_266021286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OOT43_RS14535 (OOT43_14535) 3054910..3056520 + 1611 WP_266021287.1 DNA mismatch repair protein MutS -
OOT43_RS14540 (OOT43_14540) 3056520..3057290 + 771 WP_266021288.1 hydroxyacylglutathione hydrolase -
OOT43_RS14545 (OOT43_14545) 3057287..3058696 - 1410 WP_266021289.1 amino acid permease -
OOT43_RS14550 (OOT43_14550) 3058868..3059119 + 252 WP_266021290.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 56 a.a.        Molecular weight: 6128.15 Da        Isoelectric Point: 7.1643

>T264490 WP_266021285.1 NZ_CP110921:c3054573-3054406 [Methylococcus sp. 16-5]
VILVDTSIWIDHFRAGDPLLAELLNDRRVLAHPFVAGELACGNLKNRASILSLFR

Download         Length: 168 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7310.47 Da        Isoelectric Point: 10.6826

>AT264490 WP_266021286.1 NZ_CP110921:c3054767-3054570 [Methylococcus sp. 16-5]
MRTTLNIDDRLLAEAQRMTGLVEKSVLVREGLKALVERESARRLALLAGSEPQLQNIPRRQTEPA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References