Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2148949..2149471 Replicon chromosome
Accession NZ_CP110921
Organism Methylococcus sp. 16-5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OOT43_RS10045 Protein ID WP_266024792.1
Coordinates 2148949..2149236 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OOT43_RS10050 Protein ID WP_266024793.1
Coordinates 2149226..2149471 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOT43_RS10020 (OOT43_10020) 2144070..2145644 - 1575 WP_266024784.1 class I SAM-dependent DNA methyltransferase -
OOT43_RS10025 (OOT43_10025) 2145800..2146642 - 843 WP_266024785.1 DUF3037 domain-containing protein -
OOT43_RS10030 (OOT43_10030) 2146639..2147373 - 735 WP_266024786.1 hypothetical protein -
OOT43_RS10035 (OOT43_10035) 2147370..2148797 - 1428 WP_266024788.1 restriction endonuclease subunit S -
OOT43_RS10040 (OOT43_10040) 2148794..2148952 - 159 WP_266024790.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
OOT43_RS10045 (OOT43_10045) 2148949..2149236 - 288 WP_266024792.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OOT43_RS10050 (OOT43_10050) 2149226..2149471 - 246 WP_266024793.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OOT43_RS10055 (OOT43_10055) 2149527..2152385 - 2859 WP_266024795.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
OOT43_RS10060 (OOT43_10060) 2152441..2152929 - 489 WP_266024797.1 protein disulfide oxidoreductase -
OOT43_RS10065 (OOT43_10065) 2152929..2153663 - 735 WP_266024800.1 SprT family zinc-dependent metalloprotease -
OOT43_RS10070 (OOT43_10070) 2153673..2154173 - 501 WP_266024802.1 GreA/GreB family elongation factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-71)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11140.93 Da        Isoelectric Point: 10.4470

>T264486 WP_266024792.1 NZ_CP110921:c2149236-2148949 [Methylococcus sp. 16-5]
MTYSLEFRDSAWKEWQNLDRPLHEQFKAKLLERLANPRVESARLSGLPDCYKIKLRAAGYRLVYQVFDERVVVVVVAVGK
REDSAVYRKARGRVK

Download         Length: 288 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9018.29 Da        Isoelectric Point: 4.3557

>AT264486 WP_266024793.1 NZ_CP110921:c2149471-2149226 [Methylococcus sp. 16-5]
MELLYTNASVSISELKKNPTAVIEEADGFPVAVLNHNKPAAYLVPAAAFEAMMEKLDDIELARLVRERENEPTVRVDPHD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References