Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4787282..4787948 Replicon chromosome
Accession NZ_CP110894
Organism Citrobacter freundii strain CF1807

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OQW59_RS26355 Protein ID WP_134214823.1
Coordinates 4787589..4787948 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OQW59_RS26350 Protein ID WP_134214821.1
Coordinates 4787282..4787599 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQW59_RS26310 (4782570) 4782570..4783394 + 825 WP_048216971.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
OQW59_RS26315 (4783462) 4783462..4784685 + 1224 WP_003031639.1 L-sorbose 1-phosphate reductase -
OQW59_RS26320 (4784687) 4784687..4785499 + 813 WP_148374214.1 shikimate 5-dehydrogenase -
OQW59_RS26325 (4785533) 4785533..4785850 - 318 WP_054527950.1 CcdB family protein -
OQW59_RS26330 (4785850) 4785850..4786143 - 294 WP_003844689.1 type II toxin-antitoxin system CcdA family antitoxin -
OQW59_RS26335 (4786240) 4786240..4786605 - 366 WP_134214819.1 hypothetical protein -
OQW59_RS26340 (4786737) 4786737..4786910 + 174 WP_032938222.1 hypothetical protein -
OQW59_RS26345 (4786981) 4786981..4787142 + 162 WP_003841416.1 phage protein -
OQW59_RS26350 (4787282) 4787282..4787599 - 318 WP_134214821.1 helix-turn-helix transcriptional regulator Antitoxin
OQW59_RS26355 (4787589) 4787589..4787948 - 360 WP_134214823.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQW59_RS26360 (4788162) 4788162..4788851 + 690 WP_003841421.1 dipeptidase PepE -
OQW59_RS26365 (4788998) 4788998..4790629 - 1632 WP_003031618.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13456.53 Da        Isoelectric Point: 10.2555

>T264478 WP_134214823.1 NZ_CP110894:c4787948-4787589 [Citrobacter freundii]
MTKPLYWVGQARKDLLAMPEHVRDTFGFAFWLAQQGKQHSQTKPLKGFGGAGVLEVVEDYHGSAWRAVYTIQLKNAVYVL
HVFQKKSVSGKATPKPEIDLIYQRLKAAQRHAQESGYVI

Download         Length: 360 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11504.44 Da        Isoelectric Point: 8.9375

>AT264478 WP_134214821.1 NZ_CP110894:c4787599-4787282 [Citrobacter freundii]
MSYEVEASSGNVYVDLGAYDAEQMQLKAQLAMVIGEILQRKGLTQQQAAQLLGMTQPKLSNLLRGQFRGISEAKMLECLV
RLGRDVEIVVGKEGNMSGKLKVKFG

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References