264447

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3382721..3383346 Replicon chromosome
Accession NZ_CP110887
Organism Dickeya solani strain DsR207

Toxin (Protein)


Gene name Hha Uniprot ID A0A2K8W3K4
Locus tag OQ522_RS14840 Protein ID WP_022632574.1
Coordinates 3382721..3382924 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A2K8W3I1
Locus tag OQ522_RS14845 Protein ID WP_022632575.1
Coordinates 3382978..3383346 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ522_RS14810 (OQ522_05565) 3378361..3378699 + 339 WP_002208627.1 P-II family nitrogen regulator -
OQ522_RS14815 (OQ522_05570) 3378742..3380034 + 1293 WP_022632570.1 ammonium transporter AmtB -
OQ522_RS14820 (OQ522_05575) 3380130..3380993 - 864 WP_022632571.1 acyl-CoA thioesterase II -
OQ522_RS14825 (OQ522_05580) 3381245..3381802 + 558 WP_022632572.1 YbaY family lipoprotein -
OQ522_RS14830 (OQ522_05585) 3381831..3382160 - 330 WP_022632573.1 MGMT family protein -
OQ522_RS14840 (OQ522_05595) 3382721..3382924 - 204 WP_022632574.1 HHA domain-containing protein Toxin
OQ522_RS14845 (OQ522_05600) 3382978..3383346 - 369 WP_022632575.1 Hha toxicity modulator TomB Antitoxin
OQ522_RS14850 (OQ522_05605) 3383854..3383997 - 144 WP_022632576.1 type B 50S ribosomal protein L36 -
OQ522_RS14855 (OQ522_05610) 3384013..3384264 - 252 WP_022632577.1 type B 50S ribosomal protein L31 -
OQ522_RS14860 (OQ522_05615) 3384441..3387587 - 3147 WP_022632578.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8161.52 Da        Isoelectric Point: 8.8580

>T264447 WP_022632574.1 NZ_CP110887:c3382924-3382721 [Dickeya solani]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14223.06 Da        Isoelectric Point: 5.1663

>AT264447 WP_022632575.1 NZ_CP110887:c3383346-3382978 [Dickeya solani]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSHGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDTELRKWQKSKSQLFRMFSEKSICTVVKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W3K4

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W3I1

References