264446

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2894472..2895150 Replicon chromosome
Accession NZ_CP110887
Organism Dickeya solani strain DsR207

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OQ522_RS12700 Protein ID WP_023637601.1
Coordinates 2894719..2895150 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2K8QSU7
Locus tag OQ522_RS12695 Protein ID WP_023637600.1
Coordinates 2894472..2894738 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ522_RS12675 (OQ522_03430) 2890922..2891572 + 651 WP_022632163.1 LysE family translocator -
OQ522_RS12680 (OQ522_03435) 2891643..2892251 - 609 WP_022632164.1 HD domain-containing protein -
OQ522_RS12685 (OQ522_03440) 2892461..2893111 + 651 WP_022632165.1 hemolysin III family protein -
OQ522_RS12690 (OQ522_03445) 2893185..2894165 - 981 WP_022632166.1 tRNA-modifying protein YgfZ -
OQ522_RS12695 (OQ522_03450) 2894472..2894738 + 267 WP_023637600.1 FAD assembly factor SdhE Antitoxin
OQ522_RS12700 (OQ522_03455) 2894719..2895150 + 432 WP_023637601.1 protein YgfX Toxin
OQ522_RS12705 (OQ522_03460) 2895250..2895768 - 519 WP_022632169.1 flavodoxin FldB -
OQ522_RS12710 (OQ522_03465) 2895897..2897222 - 1326 WP_022632170.1 MFS transporter -
OQ522_RS12715 (OQ522_03470) 2897485..2898384 + 900 WP_022632171.1 site-specific tyrosine recombinase XerD -
OQ522_RS12720 (OQ522_03475) 2898474..2899181 + 708 WP_022632172.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16808.51 Da        Isoelectric Point: 11.7737

>T264446 WP_023637601.1 NZ_CP110887:2894719-2895150 [Dickeya solani]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Download         Length: 432 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.03 Da        Isoelectric Point: 5.5535

>AT264446 WP_023637600.1 NZ_CP110887:2894472-2894738 [Dickeya solani]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8QSU7

References