Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2752820..2753604 Replicon chromosome
Accession NZ_CP110887
Organism Dickeya solani strain DsR207

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag OQ522_RS12015 Protein ID WP_022632047.1
Coordinates 2753110..2753604 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A2K8W1V4
Locus tag OQ522_RS12010 Protein ID WP_022632046.1
Coordinates 2752820..2753113 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQ522_RS11990 (OQ522_02745) 2748646..2749098 + 453 WP_022632042.1 hypothetical protein -
OQ522_RS11995 (OQ522_02750) 2749141..2749437 + 297 WP_022632043.1 YciI family protein -
OQ522_RS12000 (OQ522_02755) 2749465..2750172 + 708 WP_022632044.1 SDR family oxidoreductase -
OQ522_RS12005 (OQ522_02760) 2751164..2752415 - 1252 Protein_2324 tyrosine-type recombinase/integrase -
OQ522_RS12010 (OQ522_02765) 2752820..2753113 + 294 WP_022632046.1 DUF1778 domain-containing protein Antitoxin
OQ522_RS12015 (OQ522_02770) 2753110..2753604 + 495 WP_022632047.1 GNAT family N-acetyltransferase Toxin
OQ522_RS12020 (OQ522_02775) 2753656..2754053 + 398 Protein_2327 DUF3577 domain-containing protein -
OQ522_RS12025 (OQ522_02780) 2754169..2755440 + 1272 WP_022632048.1 hypothetical protein -
OQ522_RS12030 (OQ522_02785) 2755444..2756022 + 579 WP_023637591.1 hypothetical protein -
OQ522_RS12035 (OQ522_02790) 2756010..2757950 + 1941 WP_022632050.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2752577..2762908 10331


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(66-143)

Antitoxin

Vibrio phage ICP1, Orf50

(5-95)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17639.41 Da        Isoelectric Point: 6.8524

>T264444 WP_022632047.1 NZ_CP110887:2753110-2753604 [Dickeya solani]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDDSRVLAYYSLASSAVATTAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEARDFYLRVGFEPSPIDPMILMVTLGDLVG
SLSI

Download         Length: 495 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10942.53 Da        Isoelectric Point: 9.8078

>AT264444 WP_022632046.1 NZ_CP110887:2752820-2753113 [Dickeya solani]
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQAPEPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W1V4

References