Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3896336..3896993 Replicon chromosome
Accession NZ_CP110873
Organism Enterobacter kobei strain SCLZS19

Toxin (Protein)


Gene name cptA Uniprot ID A0A2W0G6Z0
Locus tag OQE50_RS18845 Protein ID WP_014885136.1
Coordinates 3896336..3896746 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag OQE50_RS18850 Protein ID WP_010435322.1
Coordinates 3896727..3896993 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQE50_RS18825 (3892330) 3892330..3894063 - 1734 WP_032635612.1 single-stranded-DNA-specific exonuclease RecJ -
OQE50_RS18830 (3894069) 3894069..3894782 - 714 WP_266071585.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OQE50_RS18835 (3894811) 3894811..3895707 - 897 WP_014885134.1 site-specific tyrosine recombinase XerD -
OQE50_RS18840 (3895809) 3895809..3896330 + 522 WP_071922917.1 flavodoxin FldB -
OQE50_RS18845 (3896336) 3896336..3896746 - 411 WP_014885136.1 protein YgfX Toxin
OQE50_RS18850 (3896727) 3896727..3896993 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
OQE50_RS18855 (3897288) 3897288..3898268 + 981 WP_014885137.1 tRNA-modifying protein YgfZ -
OQE50_RS18860 (3898353) 3898353..3899012 - 660 WP_023331242.1 hemolysin III family protein -
OQE50_RS18865 (3899278) 3899278..3900009 + 732 WP_179121345.1 MurR/RpiR family transcriptional regulator -
OQE50_RS18870 (3900126) 3900126..3901559 + 1434 WP_014885140.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16135.04 Da        Isoelectric Point: 10.7510

>T264422 WP_014885136.1 NZ_CP110873:c3896746-3896336 [Enterobacter kobei]
VVLWQSDLRVSWRSQWMSLMLHGLVAAIVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNSGMMLRLRNVDGGRCQHLWLAADSMDASEWRDLRRMLLQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT264422 WP_010435322.1 NZ_CP110873:c3896993-3896727 [Enterobacter kobei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2W0G6Z0

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References