Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 3184965..3185548 Replicon chromosome
Accession NZ_CP110848
Organism Trichothermofontia sichuanensis PKUAC-SCTB231

Toxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OOK60_RS13560 Protein ID WP_265901038.1
Coordinates 3184965..3185294 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OOK60_RS13565 Protein ID WP_265901039.1
Coordinates 3185282..3185548 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOK60_RS13550 (OOK60_13550) 3180450..3180738 + 289 Protein_2666 transposase -
OOK60_RS13555 (OOK60_13555) 3180881..3184924 + 4044 WP_265901037.1 hypothetical protein -
OOK60_RS13560 (OOK60_13560) 3184965..3185294 - 330 WP_265901038.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OOK60_RS13565 (OOK60_13565) 3185282..3185548 - 267 WP_265901039.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OOK60_RS13570 (OOK60_13570) 3186191..3187780 - 1590 WP_265901040.1 calcium-binding protein -
OOK60_RS13575 (OOK60_13575) 3188337..3189434 - 1098 WP_265904197.1 calcium-binding protein -
OOK60_RS13580 (OOK60_13580) 3189609..3189971 + 363 WP_265901041.1 hypothetical protein -
OOK60_RS13585 (OOK60_13585) 3190187..3190336 - 150 WP_265901042.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-107)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12423.47 Da        Isoelectric Point: 5.1828

>T264373 WP_265901038.1 NZ_CP110848:c3185294-3184965 [Trichothermofontia sichuanensis PKUAC-SCTB231]
MGLVVQRFDVFLVNLDPTVGREIQKARPCVVISPDEMNRYIDTVIIAPMTTEGKAYPTRVICQFQGKDGQIVLDQIRTID
KRRLVKKLGQISQDEQKEVLDTLAEMFAE

Download         Length: 330 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10242.54 Da        Isoelectric Point: 5.1408

>AT264373 WP_265901039.1 NZ_CP110848:c3185548-3185282 [Trichothermofontia sichuanensis PKUAC-SCTB231]
MIRTRIIKIGNSQGVRIPKLLLEQSGIQAEVDQAEVEIEVQGNHLTIRAAPHRREGWDDAFATMAKRKDDRLLDEVTPNH
WDQVEWDW

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References