264372

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 1951543..1952180 Replicon chromosome
Accession NZ_CP110848
Organism Trichothermofontia sichuanensis PKUAC-SCTB231

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OOK60_RS08310 Protein ID WP_265903879.1
Coordinates 1951543..1951938 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OOK60_RS08315 Protein ID WP_265903880.1
Coordinates 1951935..1952180 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOK60_RS08300 (OOK60_08300) 1947272..1949863 + 2592 WP_265903877.1 leucine--tRNA ligase -
OOK60_RS08305 (OOK60_08305) 1950848..1951345 + 498 WP_265903878.1 hypothetical protein -
OOK60_RS08310 (OOK60_08310) 1951543..1951938 - 396 WP_265903879.1 type II toxin-antitoxin system VapC family toxin Toxin
OOK60_RS08315 (OOK60_08315) 1951935..1952180 - 246 WP_265903880.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OOK60_RS08320 (OOK60_08320) 1952231..1952656 - 426 WP_265904150.1 MAPEG family protein -
OOK60_RS08325 (OOK60_08325) 1952672..1953925 - 1254 WP_265904151.1 tryptophan synthase subunit beta -
OOK60_RS08330 (OOK60_08330) 1954115..1954351 + 237 WP_265903881.1 hypothetical protein -
OOK60_RS08335 (OOK60_08335) 1954666..1955232 - 567 WP_265903882.1 hypothetical protein -
OOK60_RS08340 (OOK60_08340) 1955706..1956485 - 780 WP_265903883.1 iron export ABC transporter permease subunit FetB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(4-127)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14996.11 Da        Isoelectric Point: 4.2386

>T264372 WP_265903879.1 NZ_CP110848:c1951938-1951543 [Trichothermofontia sichuanensis PKUAC-SCTB231]
VKLLLDTQCWLWWFAQPEKLNENVIEQIADETNEVWFSVMSIWEMGIKVSIGKLSLPEQIDDYISSRMTQLGARSLEITA
SHALRVAALLHHRDPFDQMLIAQAQVEEMTLVSADSTFNQYEVSLLWAANS

Download         Length: 396 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8978.26 Da        Isoelectric Point: 4.7205

>AT264372 WP_265903880.1 NZ_CP110848:c1952180-1951935 [Trichothermofontia sichuanensis PKUAC-SCTB231]
METVNIHQAKTNLSRLLSRVELGEEIVIANRGIPIAKLVPFRTSLDRRSSLGQDRGMFTVPDDFNVPLPEDILVAFDGSA
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References