Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 355026..355696 Replicon plasmid pAt13-2099-1-2a
Accession NZ_CP110833
Organism Agrobacterium sp. 13-2099-1-2

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E8LLV6
Locus tag A6U84_RS24405 Protein ID WP_065662736.1
Coordinates 355277..355696 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E8LL22
Locus tag A6U84_RS24400 Protein ID WP_065703160.1
Coordinates 355026..355280 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U84_RS24390 (A6U84_24390) 352322..353329 + 1008 WP_065703158.1 sensor histidine kinase -
A6U84_RS24395 (A6U84_24395) 354040..354645 - 606 WP_065703247.1 J domain-containing protein -
A6U84_RS24400 (A6U84_24400) 355026..355280 + 255 WP_065703160.1 plasmid stabilization protein Antitoxin
A6U84_RS24405 (A6U84_24405) 355277..355696 + 420 WP_065662736.1 type II toxin-antitoxin system VapC family toxin Toxin
A6U84_RS24410 (A6U84_24410) 355836..356732 - 897 WP_013637432.1 dihydrodipicolinate synthase family protein -
A6U84_RS24415 (A6U84_24415) 356765..357646 - 882 WP_065662737.1 SMP-30/gluconolactonase/LRE family protein -
A6U84_RS24420 (A6U84_24420) 357702..358421 - 720 WP_003517195.1 FCD domain-containing protein -
A6U84_RS24425 (A6U84_24425) 358721..360670 + 1950 WP_065703162.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..611263 611263


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15050.25 Da        Isoelectric Point: 5.1532

>T264368 WP_065662736.1 NZ_CP110833:355277-355696 [Agrobacterium sp. 13-2099-1-2]
MILLDTNVISEPWKPIPDEAVIAWLDAQAVETLFISAITIAELRFGIAAMPSGRRQTILRDRLEGEVLPHFSGRILSFDL
TTSQFYSELMARARASGKAIGTADGYIAATAAANGLTISTRDTSPFEAAGVKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9328.60 Da        Isoelectric Point: 10.4369

>AT264368 WP_065703160.1 NZ_CP110833:355026-355280 [Agrobacterium sp. 13-2099-1-2]
MRAVTIRNLSEETHRALRVRAAHHGRSTEAEIRAIIEAAVRPPERIQLGSLLAAIGRDAELSNSDVEALQKSRDKTPSKP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References