264366

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 318297..318759 Replicon chromosome
Accession NZ_CP110831
Organism Agrobacterium sp. 13-2099-1-2

Toxin (Protein)


Gene name pasB Uniprot ID A0A9E8LFT7
Locus tag A6U84_RS01500 Protein ID WP_065703878.1
Coordinates 318297..318548 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID F0L6V5
Locus tag A6U84_RS01505 Protein ID WP_013635548.1
Coordinates 318532..318759 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U84_RS01470 (A6U84_01470) 313334..314107 - 774 WP_065658316.1 L,D-transpeptidase -
A6U84_RS01475 (A6U84_01475) 314345..314975 + 631 Protein_288 DNA-3-methyladenine glycosylase I -
A6U84_RS01480 (A6U84_01480) 314972..315415 + 444 WP_013635544.1 hypothetical protein -
A6U84_RS01485 (A6U84_01485) 315431..316474 - 1044 WP_065703874.1 YeiH family protein -
A6U84_RS01490 (A6U84_01490) 316557..317474 + 918 WP_004432220.1 LysR substrate-binding domain-containing protein -
A6U84_RS01495 (A6U84_01495) 317526..318290 - 765 WP_065703876.1 hypothetical protein -
A6U84_RS01500 (A6U84_01500) 318297..318548 - 252 WP_065703878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6U84_RS01505 (A6U84_01505) 318532..318759 - 228 WP_013635548.1 DUF6290 family protein Antitoxin
A6U84_RS01510 (A6U84_01510) 318916..320541 + 1626 WP_065703880.1 histidine--tRNA ligase -
A6U84_RS01515 (A6U84_01515) 320546..320914 + 369 WP_026330619.1 VOC family protein -
A6U84_RS01520 (A6U84_01520) 320931..322058 + 1128 WP_004432209.1 ATP phosphoribosyltransferase regulatory subunit -
A6U84_RS01525 (A6U84_01525) 322055..322747 + 693 WP_004432208.1 ATP phosphoribosyltransferase -
A6U84_RS01530 (A6U84_01530) 322811..323257 - 447 WP_065703882.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-82)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9851.38 Da        Isoelectric Point: 9.5687

>T264366 WP_065703878.1 NZ_CP110831:c318548-318297 [Agrobacterium sp. 13-2099-1-2]
VIWTIEYDVLVQKEMRKIDPQTRQRIRVAALDNPRQTGAALQGSELGSFWRYRVGDYRIICDIQDHKLVVLVVEIGHRRE
IYR

Download         Length: 252 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8909.92 Da        Isoelectric Point: 4.7254

>AT264366 WP_013635548.1 NZ_CP110831:c318759-318532 [Agrobacterium sp. 13-2099-1-2]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRIQRGESKVVSAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0L6V5

References