Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 3728181..3728880 Replicon chromosome
Accession NZ_CP110823
Organism Enterobacter roggenkampii strain WS22-2

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag OM419_RS17375 Protein ID WP_090392716.1
Coordinates 3728181..3728504 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag OM419_RS17380 Protein ID WP_277737894.1
Coordinates 3728524..3728880 (-) Length 119 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM419_RS17370 (OM419_17365) 3725892..3727556 - 1665 WP_277737893.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -
OM419_RS17375 (OM419_17370) 3728181..3728504 - 324 WP_090392716.1 TA system toxin CbtA family protein Toxin
OM419_RS17380 (OM419_17375) 3728524..3728880 - 357 WP_277737894.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
OM419_RS17385 (OM419_17380) 3728906..3729127 - 222 Protein_3398 DUF987 family protein -
OM419_RS17390 (OM419_17385) 3729124..3729666 - 543 WP_277737895.1 DNA repair protein RadC -
OM419_RS17395 (OM419_17390) 3729679..3730128 - 450 WP_277737896.1 antirestriction protein -
OM419_RS17400 (OM419_17395) 3730159..3730980 - 822 WP_277737897.1 DUF932 domain-containing protein -
OM419_RS17405 (OM419_17400) 3731083..3731316 - 234 WP_277718033.1 DUF905 domain-containing protein -
OM419_RS17410 (OM419_17405) 3731410..3732246 - 837 WP_277718034.1 hypothetical protein -
OM419_RS17415 (OM419_17410) 3732304..3732549 - 246 WP_277718035.1 hypothetical protein -
OM419_RS17420 (OM419_17415) 3732549..3732776 - 228 WP_277718036.1 hypothetical protein -
OM419_RS17425 (OM419_17420) 3732849..3733256 - 408 WP_211778063.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - fimA / fimC / fimD / fimF / fimG 3728181..3755439 27258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-107)

Antitoxin

(17-117)


Sequences


Toxin        


Download         Length: 108 a.a.        Molecular weight: 12313.16 Da        Isoelectric Point: 6.2134

>T264364 WP_090392716.1 NZ_CP110823:c3728504-3728181 [Enterobacter roggenkampii]
MKYQPATTLWAAKPSLSPVAVWQMLLTRLLEQHYGLTLNDTPFCDETVIQEHIDAGITLANAVNFLVEKYELARIDHRGF
GWNEQTPYLTIVDIMRARRDLGLLNRN

Download         Length: 324 bp


Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13128.73 Da        Isoelectric Point: 5.4242

>AT264364 WP_277737894.1 NZ_CP110823:c3728880-3728524 [Enterobacter roggenkampii]
MNNHSESGTGPENPACQQWGLKSTITPYFGARLVQEGYRVHFLADRAGFTGALSEDDALHLDQVFPLILKQLELMFTSGE
LSSRHQHCVTLYHNGLTCEADTLGSCGYIYIAIYPTQY

Download         Length: 357 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References