Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1956234..1956505 Replicon chromosome
Accession NZ_CP110814
Organism Escherichia coli strain THB42-F4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1956364..1956467 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1956234..1956505 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0552_RS09355 1952789..1953451 - 663 WP_000944256.1 exodeoxyribonuclease X -
N0552_RS09360 1953475..1954131 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N0552_RS09365 1954233..1954463 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N0552_RS09370 1954602..1954976 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N0552_RS09375 1954980..1955852 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
N0552_RS09380 1955865..1956206 + 342 WP_000976476.1 YebY family protein -
- 1956234..1956505 - 272 - - Antitoxin
- 1956364..1956467 + 104 - - Toxin
N0552_RS09385 1956602..1957258 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
N0552_RS09390 1957259..1957450 - 192 WP_000457842.1 YebW family protein -
N0552_RS09395 1957555..1957791 - 237 WP_001295499.1 YebV family protein -
N0552_RS09400 1957909..1959348 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T264302 NZ_CP110814:1956364-1956467 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT264302 NZ_CP110814:c1956505-1956234 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References