Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1378472..1379391 Replicon chromosome
Accession NZ_CP110812
Organism Bacillus paralicheniformis strain CamBx3

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag OPU65_RS07090 Protein ID WP_165426770.1
Coordinates 1378472..1379218 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag OPU65_RS07095 Protein ID WP_265627258.1
Coordinates 1379218..1379391 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPU65_RS07070 (OPU65_07070) 1373865..1374509 - 645 WP_265627257.1 YesL family protein -
OPU65_RS07075 (OPU65_07075) 1374644..1376401 - 1758 WP_165426773.1 gamma-glutamyltransferase -
OPU65_RS07080 (OPU65_07080) 1376734..1377351 + 618 WP_165426772.1 DUF47 domain-containing protein -
OPU65_RS07085 (OPU65_07085) 1377364..1378362 + 999 WP_026586618.1 inorganic phosphate transporter -
OPU65_RS07090 (OPU65_07090) 1378472..1379218 + 747 WP_165426770.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OPU65_RS07095 (OPU65_07095) 1379218..1379391 + 174 WP_265627258.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OPU65_RS07100 (OPU65_07100) 1379487..1379618 + 132 WP_265627259.1 hypothetical protein -
OPU65_RS07105 (OPU65_07105) 1379687..1380958 - 1272 WP_265627260.1 MFS transporter -
OPU65_RS07110 (OPU65_07110) 1381010..1382021 - 1012 Protein_1417 zinc-binding alcohol dehydrogenase family protein -
OPU65_RS07115 (OPU65_07115) 1382049..1382897 - 849 WP_265627261.1 SDR family oxidoreductase -
OPU65_RS07120 (OPU65_07120) 1382873..1383970 - 1098 WP_265627262.1 mannonate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29434.91 Da        Isoelectric Point: 4.6664

>T264290 WP_165426770.1 NZ_CP110812:1378472-1379218 [Bacillus paralicheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDN

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6861.91 Da        Isoelectric Point: 10.7562

>AT264290 WP_265627258.1 NZ_CP110812:1379218-1379391 [Bacillus paralicheniformis]
MEPAFQQDQESAKTRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References