Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 20177..20624 Replicon plasmid pMUP32b
Accession NZ_CP110811
Organism Pseudomonas syringae strain MUP32

Toxin (Protein)


Gene name relE Uniprot ID A0A3M4C5F0
Locus tag OQB64_RS26730 Protein ID WP_003348606.1
Coordinates 20177..20449 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4C5H0
Locus tag OQB64_RS26735 Protein ID WP_005730485.1
Coordinates 20439..20624 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB64_RS26730 (OQB64_26730) 20177..20449 - 273 WP_003348606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQB64_RS26735 (OQB64_26735) 20439..20624 - 186 WP_005730485.1 hypothetical protein Antitoxin
OQB64_RS26740 (OQB64_26740) 20675..20953 - 279 WP_003320513.1 hypothetical protein -
OQB64_RS26745 (OQB64_26745) 21046..21177 - 132 Protein_25 resolvase -
OQB64_RS26750 (OQB64_26750) 21611..21937 - 327 WP_003319696.1 type II toxin-antitoxin system PemK/MazF family toxin -
OQB64_RS26755 (OQB64_26755) 21934..22158 - 225 WP_003319697.1 antitoxin MazE family protein -
OQB64_RS26760 (OQB64_26760) 22648..23280 + 633 WP_003381804.1 ParA family protein -
OQB64_RS26765 (OQB64_26765) 23316..23570 + 255 WP_003381801.1 hypothetical protein -
OQB64_RS26770 (OQB64_26770) 23995..24660 - 666 WP_024647998.1 LexA family transcriptional regulator -
OQB64_RS26775 (OQB64_26775) 24748..24978 + 231 WP_010215521.1 Cro/CI family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..54993 54993


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10199.67 Da        Isoelectric Point: 5.0749

>T264288 WP_003348606.1 NZ_CP110811:c20449-20177 [Pseudomonas syringae]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIL
DVLHARQEYP

Download         Length: 273 bp

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7292.18 Da        Isoelectric Point: 7.2040

>AT264288 WP_005730485.1 NZ_CP110811:c20624-20439 [Pseudomonas syringae]
MSIQLDPRVSEFETQEQADNYDRWFRQRIEHSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4C5F0

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4C5H0

References