Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 12995..13606 Replicon plasmid pMUP32b
Accession NZ_CP110811
Organism Pseudomonas syringae strain MUP32

Toxin (Protein)


Gene name PfiT Uniprot ID A0A7Z6UVP4
Locus tag OQB64_RS26720 Protein ID WP_003348598.1
Coordinates 13256..13606 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q48B86
Locus tag OQB64_RS26715 Protein ID WP_004662018.1
Coordinates 12995..13243 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB64_RS26690 (OQB64_26690) 8549..8836 + 288 WP_003348585.1 hypothetical protein -
OQB64_RS26695 (OQB64_26695) 9048..9689 + 642 WP_110768561.1 SOS response-associated peptidase -
OQB64_RS26700 (OQB64_26700) 9877..10452 + 576 WP_003348590.1 PBECR2 nuclease fold domain-containing protein -
OQB64_RS26705 (OQB64_26705) 11390..12364 - 975 WP_080271137.1 tyrosine-type recombinase/integrase -
OQB64_RS26710 (OQB64_26710) 12393..12755 - 363 WP_124733765.1 hypothetical protein -
OQB64_RS26715 (OQB64_26715) 12995..13243 + 249 WP_004662018.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OQB64_RS26720 (OQB64_26720) 13256..13606 + 351 WP_003348598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..54993 54993


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12994.80 Da        Isoelectric Point: 4.1953

>T264287 WP_003348598.1 NZ_CP110811:13256-13606 [Pseudomonas syringae]
MNTFALRFTEVAQQSLEDQVEHLAVYQGFSSAAQRIDSLIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSDGINDIAVLLVLGGKQSVEQALIRYCLLQPM

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9352.70 Da        Isoelectric Point: 9.8450

>AT264287 WP_004662018.1 NZ_CP110811:12995-13243 [Pseudomonas syringae]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFA
QK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z6UVP4

Antitoxin

Source ID Structure
AlphaFold DB A0A0N8T3U9

References