Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4354542..4355004 Replicon chromosome
Accession NZ_CP110809
Organism Pseudomonas syringae strain MUP32

Toxin (Protein)


Gene name relE Uniprot ID A0A0P9XJI4
Locus tag OQB64_RS19310 Protein ID WP_003393317.1
Coordinates 4354723..4355004 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M2UJ05
Locus tag OQB64_RS19305 Protein ID WP_003393315.1
Coordinates 4354542..4354733 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB64_RS19285 (OQB64_19285) 4350398..4351252 + 855 WP_080270898.1 XopAF/AvrXv3 family type III secretion system effector -
OQB64_RS19290 (OQB64_19290) 4351256..4351634 - 379 Protein_3794 transposase -
OQB64_RS19295 (OQB64_19295) 4351897..4353009 - 1113 WP_024647935.1 hypothetical protein -
OQB64_RS19300 (OQB64_19300) 4353169..4354479 + 1311 WP_124733734.1 mechanosensitive ion channel family protein -
OQB64_RS19305 (OQB64_19305) 4354542..4354733 + 192 WP_003393315.1 hypothetical protein Antitoxin
OQB64_RS19310 (OQB64_19310) 4354723..4355004 + 282 WP_003393317.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQB64_RS19315 (OQB64_19315) 4355282..4357402 + 2121 WP_122287600.1 alpha/beta hydrolase domain-containing protein -
OQB64_RS19320 (OQB64_19320) 4357573..4358613 + 1041 WP_024647852.1 DUF4062 domain-containing protein -
OQB64_RS19325 (OQB64_19325) 4358966..4359472 - 507 WP_003402417.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4348217..4361506 13289


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10563.26 Da        Isoelectric Point: 9.7428

>T264284 WP_003393317.1 NZ_CP110809:4354723-4355004 [Pseudomonas syringae]
MLVEWRPAARMNLKQILSYIADRNIRAASELGMAIEVATSALPQHPYLYRHGRVHGTREIVVHPNYLVVYKVTDRIEVLA
VLHARQAYPTDAG

Download         Length: 282 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 6977.73 Da        Isoelectric Point: 4.2322

>AT264284 WP_003393315.1 NZ_CP110809:4354542-4354733 [Pseudomonas syringae]
MSARISPIVSEFETEEQAASYDKWFRAQVQASINDPAPNISHDQVMAEMRALLESKQPPSDAG

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9XJI4

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2UJ05

References