Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2089653..2090166 Replicon chromosome
Accession NZ_CP110809
Organism Pseudomonas syringae strain MUP32

Toxin (Protein)


Gene name relE Uniprot ID A0A7Z6Y8M4
Locus tag OQB64_RS09485 Protein ID WP_003348947.1
Coordinates 2089653..2089937 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4E5F0
Locus tag OQB64_RS09490 Protein ID WP_024648170.1
Coordinates 2089927..2090166 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB64_RS09470 (OQB64_09470) 2085795..2087723 + 1929 WP_024648167.1 methyl-accepting chemotaxis protein -
OQB64_RS09475 (OQB64_09475) 2087757..2088689 - 933 WP_024648168.1 DMT family transporter -
OQB64_RS09480 (OQB64_09480) 2088764..2089618 + 855 WP_024648169.1 LysR family transcriptional regulator -
OQB64_RS09485 (OQB64_09485) 2089653..2089937 - 285 WP_003348947.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQB64_RS09490 (OQB64_09490) 2089927..2090166 - 240 WP_024648170.1 CopG family ribbon-helix-helix protein Antitoxin
OQB64_RS09495 (OQB64_09495) 2090326..2091342 - 1017 WP_003423368.1 1-aminocyclopropane-1-carboxylate deaminase -
OQB64_RS09500 (OQB64_09500) 2091529..2092035 + 507 WP_003315203.1 Lrp/AsnC family transcriptional regulator -
OQB64_RS09505 (OQB64_09505) 2092182..2093090 + 909 WP_003423371.1 DUF808 domain-containing protein -
OQB64_RS09510 (OQB64_09510) 2093267..2094052 - 786 WP_003423373.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10602.32 Da        Isoelectric Point: 10.4249

>T264282 WP_003348947.1 NZ_CP110809:c2089937-2089653 [Pseudomonas syringae]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHARRQSPPVW

Download         Length: 285 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8715.80 Da        Isoelectric Point: 4.4354

>AT264282 WP_024648170.1 NZ_CP110809:c2090166-2089927 [Pseudomonas syringae]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASQEDVKAVMDKWSGNAG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z6Y8M4

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4E5F0

References