264278

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 5273982..5274593 Replicon chromosome
Accession NZ_CP110807
Organism Pseudomonas syringae strain MUP17

Toxin (Protein)


Gene name PfiT Uniprot ID Q4ZME8
Locus tag OQB66_RS22640 Protein ID WP_003304103.1
Coordinates 5273982..5274332 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q4ZME7
Locus tag OQB66_RS22645 Protein ID WP_002556076.1
Coordinates 5274345..5274593 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB66_RS22615 (OQB66_22615) 5269091..5269933 + 843 WP_266065036.1 phage replication protein -
OQB66_RS22620 (OQB66_22620) 5270000..5270290 + 291 WP_003422698.1 TraK family protein -
OQB66_RS22625 (OQB66_22625) 5270569..5270943 + 375 WP_003316229.1 conjugal transfer transcriptional regulator TraJ -
OQB66_RS22630 (OQB66_22630) 5270986..5271741 + 756 WP_266065039.1 P-type conjugative transfer protein TrbJ -
OQB66_RS22635 (OQB66_22635) 5271945..5273330 + 1386 WP_003422693.1 P-type conjugative transfer protein TrbL -
OQB66_RS22640 (OQB66_22640) 5273982..5274332 - 351 WP_003304103.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQB66_RS22645 (OQB66_22645) 5274345..5274593 - 249 WP_002556076.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OQB66_RS22650 (OQB66_22650) 5274930..5275892 + 963 WP_004415744.1 tyrosine-type recombinase/integrase -
OQB66_RS22655 (OQB66_22655) 5276018..5276278 - 261 WP_266065044.1 hypothetical protein -
OQB66_RS22660 (OQB66_22660) 5276544..5276759 - 216 WP_003316224.1 hypothetical protein -
OQB66_RS22665 (OQB66_22665) 5276952..5277410 - 459 WP_003429427.1 helix-turn-helix domain-containing protein -
OQB66_RS22670 (OQB66_22670) 5277507..5278454 + 948 WP_003173940.1 aromatic alcohol reductase -
OQB66_RS22675 (OQB66_22675) 5278648..5278968 - 321 WP_025168236.1 hypothetical protein -
OQB66_RS22680 (OQB66_22680) 5279015..5279290 - 276 WP_025168237.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5268868..5281313 12445
- inside Prophage - - 5192139..5275892 83753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-98)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12973.76 Da        Isoelectric Point: 4.7690

>T264278 WP_003304103.1 NZ_CP110807:c5274332-5273982 [Pseudomonas syringae]
MNTFALRFTDVAQQSLEDQVEHLAVHQGFSSAAQRIDTLIDAIQDKLLSTPLGYPVSHQLSELGVLHYRELNTDGYRIFY
EVRDAGDINVIVVALVLGSKQSVEQALIRYCLLQAI

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.73 Da        Isoelectric Point: 9.9579

>AT264278 WP_002556076.1 NZ_CP110807:c5274593-5274345 [Pseudomonas syringae]
MRVETISFLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFT
QK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GDS9

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9GM89

References