Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1996937..1997450 Replicon chromosome
Accession NZ_CP110807
Organism Pseudomonas syringae strain MUP17

Toxin (Protein)


Gene name relE Uniprot ID A0A0P9GC66
Locus tag OQB66_RS08970 Protein ID WP_003423365.1
Coordinates 1996937..1997221 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9IXK3
Locus tag OQB66_RS08975 Protein ID WP_004418474.1
Coordinates 1997211..1997450 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQB66_RS08955 (OQB66_08955) 1992937..1994865 + 1929 WP_016567635.1 methyl-accepting chemotaxis protein -
OQB66_RS08960 (OQB66_08960) 1995041..1995973 - 933 WP_266066879.1 DMT family transporter -
OQB66_RS08965 (OQB66_08965) 1996048..1996902 + 855 WP_029572166.1 LysR family transcriptional regulator -
OQB66_RS08970 (OQB66_08970) 1996937..1997221 - 285 WP_003423365.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OQB66_RS08975 (OQB66_08975) 1997211..1997450 - 240 WP_004418474.1 CopG family ribbon-helix-helix protein Antitoxin
OQB66_RS08980 (OQB66_08980) 1997610..1998626 - 1017 WP_003423368.1 1-aminocyclopropane-1-carboxylate deaminase -
OQB66_RS08985 (OQB66_08985) 1998813..1999319 + 507 WP_003315203.1 Lrp/AsnC family transcriptional regulator -
OQB66_RS08990 (OQB66_08990) 1999466..2000374 + 909 WP_003423371.1 DUF808 domain-containing protein -
OQB66_RS08995 (OQB66_08995) 2000551..2001336 - 786 WP_003396313.1 outer membrane protein OmpK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10632.34 Da        Isoelectric Point: 10.4249

>T264275 WP_003423365.1 NZ_CP110807:c1997221-1996937 [Pseudomonas syringae]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Download         Length: 285 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8670.76 Da        Isoelectric Point: 4.4217

>AT264275 WP_004418474.1 NZ_CP110807:c1997450-1997211 [Pseudomonas syringae]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASPDDVKAVMDKWSGNAG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GC66

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9IXK3

References