Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 4178300..4178967 Replicon chromosome
Accession NZ_CP110806
Organism Cellulomonas sp. S1-8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OKX07_RS18815 Protein ID WP_265629529.1
Coordinates 4178300..4178692 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OKX07_RS18820 Protein ID WP_265629530.1
Coordinates 4178695..4178967 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKX07_RS18790 (OKX07_18790) 4174018..4174242 - 225 WP_265629524.1 hypothetical protein -
OKX07_RS18795 (OKX07_18795) 4174455..4174703 + 249 WP_265629525.1 hypothetical protein -
OKX07_RS18800 (OKX07_18800) 4174770..4175033 - 264 WP_265629526.1 alpha-mannosidase -
OKX07_RS18805 (OKX07_18805) 4175056..4175712 - 657 WP_265629527.1 hypothetical protein -
OKX07_RS18810 (OKX07_18810) 4175763..4178057 - 2295 WP_265629528.1 hypothetical protein -
OKX07_RS18815 (OKX07_18815) 4178300..4178692 - 393 WP_265629529.1 type II toxin-antitoxin system VapC family toxin Toxin
OKX07_RS18820 (OKX07_18820) 4178695..4178967 - 273 WP_265629530.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OKX07_RS18825 (OKX07_18825) 4179071..4179907 - 837 WP_265629531.1 EI24 domain-containing protein -
OKX07_RS18830 (OKX07_18830) 4179935..4181290 - 1356 WP_265631961.1 APC family permease -
OKX07_RS18835 (OKX07_18835) 4181674..4181829 + 156 WP_265629532.1 hypothetical protein -
OKX07_RS18840 (OKX07_18840) 4181826..4183274 + 1449 WP_265629533.1 basic amino acid/polyamine antiporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13922.97 Da        Isoelectric Point: 5.9728

>T264273 WP_265629529.1 NZ_CP110806:c4178692-4178300 [Cellulomonas sp. S1-8]
VAHYLDTSALVKLVVEESETAALRTWWRSHGSTPVACDLVRTELMRAVRRAAPHAAVQAHRVLDALVLLSVTSRVFEVAG
RLEPTTLRSLDAIHVAAALELGDDLEGLVTYDDRLAVAASAYGIAVLAPA

Download         Length: 393 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9442.69 Da        Isoelectric Point: 4.7247

>AT264273 WP_265629530.1 NZ_CP110806:c4178967-4178695 [Cellulomonas sp. S1-8]
MTMIGIRELKQNASAVVARVAAGETLTVTDRGRPTAQLSPLPTSPLARLLQSGAARPARTDLADAPTPLAPEPGEPSLSE
TLADLRDDER

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References