Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpK-mazE/MazF(toxin)
Location 4102838..4103418 Replicon chromosome
Accession NZ_CP110806
Organism Cellulomonas sp. S1-8

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag OKX07_RS18475 Protein ID WP_265629462.1
Coordinates 4103077..4103418 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OKX07_RS18470 Protein ID WP_265629461.1
Coordinates 4102838..4103080 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKX07_RS18445 (OKX07_18445) 4098407..4099345 - 939 WP_265629457.1 CPBP family intramembrane metalloprotease -
OKX07_RS18450 (OKX07_18450) 4099433..4099858 - 426 WP_265629458.1 MarR family transcriptional regulator -
OKX07_RS18455 (OKX07_18455) 4099994..4101118 + 1125 WP_265629459.1 alkene reductase -
OKX07_RS18460 (OKX07_18460) 4101200..4101856 - 657 WP_265629460.1 SDR family oxidoreductase -
OKX07_RS18465 (OKX07_18465) 4101856..4102647 - 792 WP_265631959.1 SDR family oxidoreductase -
OKX07_RS18470 (OKX07_18470) 4102838..4103080 + 243 WP_265629461.1 ribbon-helix-helix protein, CopG family Antitoxin
OKX07_RS18475 (OKX07_18475) 4103077..4103418 + 342 WP_265629462.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OKX07_RS18480 (OKX07_18480) 4103468..4107136 + 3669 WP_265629463.1 TM0106 family RecB-like putative nuclease -
OKX07_RS18485 (OKX07_18485) 4107191..4107733 + 543 WP_265629464.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-39)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 11717.36 Da        Isoelectric Point: 4.6360

>T264272 WP_265629462.1 NZ_CP110806:4103077-4103418 [Cellulomonas sp. S1-8]
VIDRGSVCWVDFGEPRGSEPGKQRPAVVVQADDFNRSAIGTVVVVPLTSNTSLAAVPGNVFVPRVASGLAKDSVANVSQV
TVASREYVTYPVASLPADLVAAIDDGLRLVLAL

Download         Length: 342 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8870.82 Da        Isoelectric Point: 7.3190

>AT264272 WP_265629461.1 NZ_CP110806:4102838-4103080 [Cellulomonas sp. S1-8]
MKTAISLPDHVAARIDASARRHGMTRSEFYRRAAERYATELERSDVTARIDAAIRTGGQPAADSAPFRSHAADVITQDEW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References