Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 647928..648598 Replicon chromosome
Accession NZ_CP110806
Organism Cellulomonas sp. S1-8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OKX07_RS03045 Protein ID WP_265630394.1
Coordinates 647928..648329 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OKX07_RS03050 Protein ID WP_265630395.1
Coordinates 648326..648598 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKX07_RS03020 (OKX07_03020) 643585..644343 - 759 WP_265630389.1 LysR substrate-binding domain-containing protein -
OKX07_RS03025 (OKX07_03025) 644340..645071 - 732 WP_265630390.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
OKX07_RS03030 (OKX07_03030) 645095..645874 - 780 WP_265630391.1 VOC family protein -
OKX07_RS03035 (OKX07_03035) 646006..647019 - 1014 WP_265630392.1 alpha/beta hydrolase -
OKX07_RS03040 (OKX07_03040) 647154..647810 - 657 WP_265630393.1 histidine phosphatase family protein -
OKX07_RS03045 (OKX07_03045) 647928..648329 - 402 WP_265630394.1 type II toxin-antitoxin system VapC family toxin Toxin
OKX07_RS03050 (OKX07_03050) 648326..648598 - 273 WP_265630395.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OKX07_RS03055 (OKX07_03055) 648756..651353 + 2598 WP_265630396.1 ATP-dependent chaperone ClpB -
OKX07_RS03060 (OKX07_03060) 651499..652197 + 699 WP_265630397.1 DedA family protein -
OKX07_RS03065 (OKX07_03065) 652204..652689 - 486 WP_265630398.1 septum formation family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-89)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14401.33 Da        Isoelectric Point: 4.9529

>T264269 WP_265630394.1 NZ_CP110806:c648329-647928 [Cellulomonas sp. S1-8]
VIVDTSAVVAILLGEPGADELVRSVLADPRPRMSAPTFVELSAVVAQKGAPQQRRRVESLLERLGIEVVAMTPEHARIAA
DAYRELGRGSGHPARLNLGDCFSYALATEQDEPLLFVGDDFSHTDLRPARARD

Download         Length: 402 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10013.24 Da        Isoelectric Point: 5.1154

>AT264269 WP_265630395.1 NZ_CP110806:c648598-648326 [Cellulomonas sp. S1-8]
MSLNIKNERTHALVRRLAELTGQSQTAAVEDAVARRLAEVESLAPVGRVDTRWADVQRLLVDYRADLSPQDRARIADADS
ALYDDLGLPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References