Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3447058..3447730 Replicon chromosome
Accession NZ_CP110791
Organism Yersinia sp. SCPM-O-B-9106 (C-191)

Toxin (Protein)


Gene name cptA Uniprot ID A0A386HHD1
Locus tag OP863_RS15750 Protein ID WP_038631074.1
Coordinates 3447058..3447483 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A386HHJ6
Locus tag OP863_RS15755 Protein ID WP_038631072.1
Coordinates 3447464..3447730 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP863_RS15730 (OP863_15730) 3442816..3443334 + 519 WP_265525523.1 flavodoxin FldB -
OP863_RS15735 (OP863_15735) 3443408..3444829 - 1422 WP_265525524.1 cell envelope integrity protein CreD -
OP863_RS15740 (OP863_15740) 3444922..3446349 - 1428 WP_145589604.1 two-component system sensor histidine kinase CreC -
OP863_RS15745 (OP863_15745) 3446360..3447058 - 699 WP_265525525.1 two-component system response regulator CreB -
OP863_RS15750 (OP863_15750) 3447058..3447483 - 426 WP_038631074.1 protein YgfX Toxin
OP863_RS15755 (OP863_15755) 3447464..3447730 - 267 WP_038631072.1 FAD assembly factor SdhE Antitoxin
OP863_RS15760 (OP863_15760) 3447997..3448989 + 993 WP_265525526.1 tRNA-modifying protein YgfZ -
OP863_RS15765 (OP863_15765) 3449038..3449721 - 684 WP_038631068.1 hemolysin III family protein -
OP863_RS15770 (OP863_15770) 3450098..3450700 + 603 WP_145589608.1 HD domain-containing protein -
OP863_RS15775 (OP863_15775) 3450713..3451462 - 750 WP_050292113.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16459.32 Da        Isoelectric Point: 10.1175

>T264264 WP_038631074.1 NZ_CP110791:c3447483-3447058 [Yersinia sp. SCPM-O-B-9106 (C-191)]
VAQWRCDLRVSWHTQLFSLLAHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNIKSCQGEIRLKPGNVVLWKRH
EWVVVKQPWITRYGVLLSLQQTSNRSTRKRLWLAADSMPEEEWRQLCLLLRHSFGSDEGIN

Download         Length: 426 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.06 Da        Isoelectric Point: 5.1405

>AT264264 WP_038631072.1 NZ_CP110791:c3447730-3447464 [Yersinia sp. SCPM-O-B-9106 (C-191)]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQVFIRLLECDDPDLFNWLMNHGEPQDSELRQMVKLIQIRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References