Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3616661..3617280 Replicon chromosome
Accession NZ_CP110790
Organism Yersinia massiliensis strain SCPM-O-B-8026 (C-146)

Toxin (Protein)


Gene name Hha Uniprot ID Q66DR5
Locus tag OP862_RS16455 Protein ID WP_002208622.1
Coordinates 3617077..3617280 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag OP862_RS16450 Protein ID WP_167311201.1
Coordinates 3616661..3617029 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP862_RS16420 (OP862_16420) 3612363..3612623 + 261 WP_167311200.1 type B 50S ribosomal protein L31 -
OP862_RS16425 (OP862_16425) 3612639..3612782 + 144 WP_002208618.1 type B 50S ribosomal protein L36 -
OP862_RS16430 (OP862_16430) 3612865..3613743 - 879 WP_050082628.1 metal ABC transporter substrate-binding protein -
OP862_RS16435 (OP862_16435) 3613772..3614629 - 858 WP_050082626.1 metal ABC transporter permease -
OP862_RS16440 (OP862_16440) 3614626..3615363 - 738 WP_050286523.1 ATP-binding cassette domain-containing protein -
OP862_RS16445 (OP862_16445) 3616149..3616502 + 354 WP_050286524.1 hypothetical protein -
OP862_RS16450 (OP862_16450) 3616661..3617029 + 369 WP_167311201.1 Hha toxicity modulator TomB Antitoxin
OP862_RS16455 (OP862_16455) 3617077..3617280 + 204 WP_002208622.1 expression modulating protein YmoA Toxin
OP862_RS16460 (OP862_16460) 3617993..3620566 - 2574 WP_050286525.1 autotransporter outer membrane beta-barrel domain-containing protein -
OP862_RS16465 (OP862_16465) 3621221..3621643 + 423 WP_050082618.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8063.31 Da        Isoelectric Point: 6.4573

>T264251 WP_002208622.1 NZ_CP110790:3617077-3617280 [Yersinia massiliensis]
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPPTVWQHVK

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14174.93 Da        Isoelectric Point: 4.4314

>AT264251 WP_167311201.1 NZ_CP110790:3616661-3617029 [Yersinia massiliensis]
MDEYSPKRHDIAQLKFLCESLYDEGIATLGDSHHGWVNDPTAAVNLQLNDLIEHIASFVMSFKIKYPDDGDLSELVEEYL
DDTYTLFSSYGINDPELRRWQKAKERLFRLFSGEYICTLMKS

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 2K5S

Antitoxin

Source ID Structure

References