Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172605..2172724 Replicon chromosome
Accession NZ_CP110790
Organism Yersinia massiliensis strain SCPM-O-B-8026 (C-146)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172624..2172716 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172605..2172724 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP862_RS09745 (OP862_09745) 2167769..2167921 - 153 WP_155410999.1 hypothetical protein -
OP862_RS09750 (OP862_09750) 2168204..2169160 + 957 WP_050285736.1 prolyl aminopeptidase -
OP862_RS09755 (OP862_09755) 2169206..2169439 - 234 WP_050285735.1 DNA polymerase III subunit theta -
OP862_RS09760 (OP862_09760) 2169833..2170342 + 510 WP_019210237.1 non-heme ferritin -
OP862_RS09765 (OP862_09765) 2170736..2171122 + 387 WP_050080589.1 CopC domain-containing protein YobA -
OP862_RS09770 (OP862_09770) 2171124..2172008 + 885 WP_050285734.1 copper homeostasis membrane protein CopD -
OP862_RS09775 (OP862_09775) 2172106..2172447 + 342 WP_050080591.1 YebY family protein -
- 2172605..2172724 - 120 - - Antitoxin
- 2172624..2172716 + 93 - - Toxin
OP862_RS09780 (OP862_09780) 2172792..2173901 - 1110 WP_167311278.1 tyrosine-type recombinase/integrase -
OP862_RS09785 (OP862_09785) 2173876..2174145 - 270 WP_050074132.1 excisionase -
OP862_RS09790 (OP862_09790) 2174252..2174620 - 369 WP_167311277.1 hypothetical protein -
OP862_RS09795 (OP862_09795) 2174790..2175053 - 264 Protein_1923 DUF550 domain-containing protein -
OP862_RS09800 (OP862_09800) 2175680..2176534 - 855 WP_167311218.1 hypothetical protein -
OP862_RS09805 (OP862_09805) 2176814..2177338 - 525 WP_167311276.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2167026..2229178 62152


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 93 bp

>T264246 NZ_CP110790:2172624-2172716 [Yersinia massiliensis]
TAAGCCTACGTTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATCGTAT
TCGGTCTTTTTTT

Antitoxin


Download         Length: 120 bp

>AT264246 NZ_CP110790:c2172724-2172605 [Yersinia massiliensis]
AACACGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTAACGTAGGCTTACTCAGCCGTACCCTTTAAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References