Detailed information of TA system TA026424

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 1932285..1932877
• Replicon: chromosome
• Accession: NC_017277
• Organism: Synechocystis sp. PCC 6803

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SYNGTS_RS09150
• Protein ID: WP_010872957.1
• Coordinates: 1932285..1932671 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SYNGTS_RS09155
• Protein ID: WP_010872958.1
• Coordinates: 1932671..1932877 (-)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNGTS_RS09140	1929956..1931128	+	1173	WP_010872955.1	sulfate adenylyltransferase	-
SYNGTS_RS09145	1931171..1932235	+	1065	WP_010872956.1	glycosyltransferase	-
SYNGTS_RS09150	1932285..1932671	-	387	WP_010872957.1	type II toxin-antitoxin system VapC family toxin	Toxin
SYNGTS_RS09155	1932671..1932877	-	207	WP_010872958.1	DUF2281 domain-containing protein	Antitoxin
SYNGTS_RS09160	1933124..1934347	-	1224	WP_010872959.1	geranylgeranyl reductase	-
SYNGTS_RS09165	1934729..1935886	+	1158	WP_010872960.1	oxidoreductase	-
SYNGTS_RS09170	1935903..1936214	+	312	WP_010872961.1	DUF433 domain-containing protein	-
SYNGTS_RS09175	1936291..1937127	+	837	WP_010872962.1	DUF1049 domain-containing protein	-
SYNGTS_RS09180	1937246..1937599	+	354	WP_010872963.1	TMEM165/GDT1 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• VapC-like Sll0205 protein, PIN domain (5-127)

Antitoxin

• Domain of unknown function DUF2281 (7-67)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 14814.14 Da
• Isoelectric Point: 6.0713

>T26424 WP_010872957.1 NC_017277:c1932671-1932285 [Synechocystis sp. PCC 6803]
MNSVLIDTHVFIWLAEDDSNLPVTTKDTLENMDNVFVSIASFWEISIKLKIGKLSLCGDFNSIEASFQRTRFKLLPITLK
DTIKLYNLPLHHKDPFDRILVSQSINHSLILVSRDQALDDYPIQRLWL

Nucleotide

• Length: 387 bp

>T26424 NC_017277:c1932671-1932285 [Synechocystis sp. PCC 6803]
ATGAATTCTGTTTTGATAGACACCCACGTTTTTATTTGGTTAGCAGAAGATGACTCTAACTTGCCTGTGACGACAAAAGA
TACCTTAGAAAATATGGATAACGTTTTTGTTAGTATTGCCAGCTTTTGGGAAATTTCTATTAAACTAAAAATTGGTAAAC
TTTCTCTCTGTGGTGATTTCAATAGTATTGAAGCTAGTTTTCAAAGAACCCGATTCAAGCTATTACCTATTACACTAAAA
GACACAATTAAACTTTATAATCTTCCCTTGCACCACAAAGATCCCTTTGATCGTATTTTGGTATCCCAATCGATTAATCA
TTCTCTTATTTTAGTCAGTCGTGATCAAGCTCTGGATGATTATCCGATTCAACGCCTGTGGTTGTAG

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7699.84 Da
• Isoelectric Point: 3.8804

>AT26424 WP_010872958.1 NC_017277:c1932877-1932671 [Synechocystis sp. PCC 6803]
MTTEAALLNIAENLPDDLKIELLHYAEYLMNKSLNAPQKPLAGSMKGTFILPLPEDFDAPLEEFEEYM

Nucleotide

• Length: 207 bp

>AT26424 NC_017277:c1932877-1932671 [Synechocystis sp. PCC 6803]
ATGACTACTGAAGCTGCCCTATTAAACATTGCTGAAAATCTGCCTGATGACTTAAAAATCGAGCTTTTACACTATGCTGA
ATATTTAATGAATAAATCCTTAAATGCGCCCCAAAAGCCATTAGCAGGATCGATGAAAGGAACTTTTATTTTACCTCTAC
CCGAAGACTTTGATGCCCCCTTAGAAGAATTTGAGGAGTATATGTAA