Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1992824..1992915 Replicon chromosome
Accession NZ_CP110789
Organism Yersinia intermedia strain SCPM-O-B-10209 (333)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1992824..1992907 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1992824..1992915 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP861_RS08800 (OP861_08800) 1988399..1989355 + 957 WP_050085883.1 prolyl aminopeptidase -
OP861_RS08805 (OP861_08805) 1989416..1989646 - 231 WP_050085884.1 DNA polymerase III subunit theta -
OP861_RS08810 (OP861_08810) 1990037..1990540 + 504 WP_005183013.1 non-heme ferritin -
OP861_RS08815 (OP861_08815) 1990928..1991314 + 387 WP_005183010.1 CopC domain-containing protein YobA -
OP861_RS08820 (OP861_08820) 1991316..1992200 + 885 WP_050085885.1 copper homeostasis membrane protein CopD -
OP861_RS08825 (OP861_08825) 1992297..1992638 + 342 WP_005183006.1 YebY family protein -
- 1992824..1992907 + 84 - - Toxin
- 1992824..1992915 - 92 - - Antitoxin
OP861_RS08830 (OP861_08830) 1992986..1994068 - 1083 WP_265535786.1 phage integrase Arm DNA-binding domain-containing protein -
OP861_RS08835 (OP861_08835) 1994043..1994309 - 267 WP_265535787.1 excisionase -
OP861_RS08840 (OP861_08840) 1994382..1994894 - 513 WP_265535788.1 siphovirus Gp157 family protein -
OP861_RS08845 (OP861_08845) 1994891..1997044 - 2154 WP_265535789.1 hypothetical protein -
OP861_RS08850 (OP861_08850) 1997058..1997330 - 273 WP_265535790.1 hypothetical protein -
OP861_RS08855 (OP861_08855) 1997561..1997893 - 333 WP_138775176.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - allB / allC / allD / flmH 1771624..2036710 265086


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 84 bp

>T264234 NZ_CP110789:1992824-1992907 [Yersinia intermedia]
ATTAATGCCAACTTTTAGCGCACGGCTCTGTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATCGTATTCGGTCTTT
TTTT

Antitoxin


Download         Length: 92 bp

>AT264234 NZ_CP110789:c1992915-1992824 [Yersinia intermedia]
AACAAGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGACAGAGCCGTGCGCTAAAA
GTTGGCATTAAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References