Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1235189..1235724 Replicon chromosome
Accession NZ_CP110789
Organism Yersinia intermedia strain SCPM-O-B-10209 (333)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OP861_RS05540 Protein ID WP_265535698.1
Coordinates 1235437..1235724 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A209ACY9
Locus tag OP861_RS05535 Protein ID WP_050084811.1
Coordinates 1235189..1235440 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP861_RS05510 (OP861_05510) 1230616..1231119 + 504 WP_050084806.1 ferredoxin-type protein NapF -
OP861_RS05515 (OP861_05515) 1231109..1231375 + 267 WP_032905977.1 chaperone NapD -
OP861_RS05520 (OP861_05520) 1231372..1233867 + 2496 WP_050133149.1 nitrate reductase catalytic subunit NapA -
OP861_RS05525 (OP861_05525) 1233963..1234430 + 468 WP_050084809.1 nitrate reductase cytochrome c-type subunit -
OP861_RS05530 (OP861_05530) 1234459..1235058 + 600 WP_042568393.1 cytochrome c-type protein NapC -
OP861_RS05535 (OP861_05535) 1235189..1235440 + 252 WP_050084811.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OP861_RS05540 (OP861_05540) 1235437..1235724 + 288 WP_265535698.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OP861_RS05545 (OP861_05545) 1235754..1236329 + 576 WP_050084918.1 GDP-mannose pyrophosphatase NudK -
OP861_RS05550 (OP861_05550) 1236665..1238944 + 2280 WP_005183822.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
OP861_RS05555 (OP861_05555) 1239123..1239581 - 459 WP_050084816.1 YaiI/YqxD family protein -
OP861_RS05560 (OP861_05560) 1239581..1240507 - 927 WP_226715690.1 oxygen-dependent coproporphyrinogen oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11042.98 Da        Isoelectric Point: 10.5833

>T264232 WP_265535698.1 NZ_CP110789:1235437-1235724 [Yersinia intermedia]
MTYAVKFREEALKEWHKLNKTIQQQFAKKLKKCSDNPHIESAKLRGMKNCYKIKLRSSGFRLVYEVIDDVLIVAVVAVGK
RDRSGVYNLASDRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9283.62 Da        Isoelectric Point: 4.3287

>AT264232 WP_050084811.1 NZ_CP110789:1235189-1235440 [Yersinia intermedia]
MPSIILTDTSASVSELKKNPMATVNAGAGFPVAILNRNQPVFYCVPAELYEQIMEALDDHELAELVNRRRHQPLLDIDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A209ACY9

References