Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 835549..836224 Replicon chromosome
Accession NZ_CP110789
Organism Yersinia intermedia strain SCPM-O-B-10209 (333)

Toxin (Protein)


Gene name cptA Uniprot ID A0A208ZYD5
Locus tag OP861_RS03700 Protein ID WP_050086374.1
Coordinates 835796..836224 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag OP861_RS03695 Protein ID WP_050086375.1
Coordinates 835549..835815 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OP861_RS03675 (OP861_03675) 831671..832420 + 750 WP_050312389.1 SDR family oxidoreductase -
OP861_RS03680 (OP861_03680) 832482..833090 - 609 WP_050086377.1 HD domain-containing protein -
OP861_RS03685 (OP861_03685) 833481..834131 + 651 WP_226717746.1 hemolysin III family protein -
OP861_RS03690 (OP861_03690) 834189..835181 - 993 WP_050086376.1 tRNA-modifying protein YgfZ -
OP861_RS03695 (OP861_03695) 835549..835815 + 267 WP_050086375.1 FAD assembly factor SdhE Antitoxin
OP861_RS03700 (OP861_03700) 835796..836224 + 429 WP_050086374.1 protein YgfX Toxin
OP861_RS03705 (OP861_03705) 836221..836916 + 696 WP_050086373.1 two-component system response regulator CreB -
OP861_RS03710 (OP861_03710) 836944..838371 + 1428 WP_050882868.1 two-component system sensor histidine kinase CreC -
OP861_RS03715 (OP861_03715) 838464..839870 + 1407 WP_050086371.1 cell envelope integrity protein CreD -
OP861_RS03720 (OP861_03720) 839921..840439 - 519 WP_005185992.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 16578.41 Da        Isoelectric Point: 10.3815

>T264231 WP_050086374.1 NZ_CP110789:835796-836224 [Yersinia intermedia]
VAQWRCDLRVSWHTQLFSLLSHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNITSCQGEIRLKPGNLVLWKRF
EWIVVKQPWITRYGVLLNLQQSSSRSARKRLWLAADSMSEDEWRQLCQLLRHSFGSDKGMNQ

Download         Length: 429 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10489.98 Da        Isoelectric Point: 5.1405

>AT264231 WP_050086375.1 NZ_CP110789:835549-835815 [Yersinia intermedia]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQAFIRLLECDDPDLFNWLMNHGEPQDNELRQMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A208ZYD5

Antitoxin

Source ID Structure

References