Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3349753..3350636 | Replicon | chromosome |
| Accession | NZ_CP110782 | ||
| Organism | Pseudomonas putida DOT-T1E | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A2K4LSC9 |
| Locus tag | OPZ46_RS15510 | Protein ID | WP_012052908.1 |
| Coordinates | 3349753..3350190 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | I7C3Q7 |
| Locus tag | OPZ46_RS15515 | Protein ID | WP_003250525.1 |
| Coordinates | 3350187..3350636 (-) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OPZ46_RS15490 (OPZ46_15490) | 3345134..3345890 | - | 757 | Protein_3058 | PAAR domain-containing protein | - |
| OPZ46_RS15495 (OPZ46_15495) | 3346054..3347283 | - | 1230 | WP_014861774.1 | acyl-CoA dehydrogenase | - |
| OPZ46_RS15500 (OPZ46_15500) | 3347424..3348347 | + | 924 | WP_014753760.1 | LysR family transcriptional regulator | - |
| OPZ46_RS15505 (OPZ46_15505) | 3348541..3349695 | + | 1155 | WP_060537721.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| OPZ46_RS15510 (OPZ46_15510) | 3349753..3350190 | - | 438 | WP_012052908.1 | RES family NAD+ phosphorylase | Toxin |
| OPZ46_RS15515 (OPZ46_15515) | 3350187..3350636 | - | 450 | WP_003250525.1 | DUF2384 domain-containing protein | Antitoxin |
| OPZ46_RS15520 (OPZ46_15520) | 3350779..3351432 | - | 654 | WP_004573726.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| OPZ46_RS15525 (OPZ46_15525) | 3351536..3352459 | + | 924 | WP_014861777.1 | LysR family transcriptional regulator | - |
| OPZ46_RS15530 (OPZ46_15530) | 3352508..3353338 | + | 831 | WP_003250518.1 | AraC family transcriptional regulator | - |
| OPZ46_RS15535 (OPZ46_15535) | 3353390..3353974 | + | 585 | WP_004573728.1 | LysE family transporter | - |
| OPZ46_RS15540 (OPZ46_15540) | 3354014..3355213 | - | 1200 | WP_014861778.1 | sugar transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15944.21 Da Isoelectric Point: 5.6016
>T264217 WP_012052908.1 NZ_CP110782:c3350190-3349753 [Pseudomonas putida DOT-T1E]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
Download Length: 438 bp
Antitoxin
Download Length: 150 a.a. Molecular weight: 16956.46 Da Isoelectric Point: 5.7258
>AT264217 WP_003250525.1 NZ_CP110782:c3350636-3350187 [Pseudomonas putida DOT-T1E]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
Download Length: 450 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A2K4LSC9 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | I7C3Q7 |