Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3354077..3354804 Replicon chromosome
Accession NZ_CP110774
Organism Acidocella sp. MX-AZ03

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag GT370_RS18545 Protein ID WP_039885796.1
Coordinates 3354286..3354804 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag GT370_RS18540 Protein ID WP_270183533.1
Coordinates 3354077..3354244 (+) Length 56 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT370_RS18525 (GT370_18500) 3350185..3351789 - 1605 WP_270183530.1 hypothetical protein -
GT370_RS18530 (GT370_18505) 3353015..3353629 - 615 WP_270183531.1 hypothetical protein -
GT370_RS18535 (GT370_18510) 3353626..3353805 - 180 WP_270183532.1 hypothetical protein -
GT370_RS18540 (GT370_18515) 3354077..3354244 + 168 WP_270183533.1 DUF1778 domain-containing protein Antitoxin
GT370_RS18545 (GT370_18520) 3354286..3354804 + 519 WP_039885796.1 GNAT family N-acetyltransferase Toxin
GT370_RS18550 (GT370_18525) 3354860..3355564 - 705 WP_270183534.1 hypothetical protein -
GT370_RS18555 (GT370_18530) 3355552..3355965 - 414 WP_270183517.1 hypothetical protein -
GT370_RS18560 (GT370_18535) 3356085..3356489 - 405 WP_270183518.1 hypothetical protein -
GT370_RS18565 (GT370_18540) 3356642..3356899 - 258 WP_270183519.1 hypothetical protein -
GT370_RS18570 (GT370_18545) 3357393..3358226 + 834 WP_008495269.1 IclR family transcriptional regulator -
GT370_RS18575 (GT370_18550) 3358508..3359772 + 1265 Protein_3649 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3330157..3365572 35415


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(57-148)

Antitoxin

Vibrio phage ICP1, Orf50

(1-45)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19049.16 Da        Isoelectric Point: 9.8224

>T264200 WP_039885796.1 NZ_CP110774:3354286-3354804 [Acidocella sp. MX-AZ03]
VRRRLLPPERLTAAHDVSGFQNGRHPSLDEWLRDRALVSEGLSARTYVVRAGEPPHLVVGYYAITTAMEQRLSLPSAKLR
RGMPEQIPLMLIGRLAVDQRYHGIGLGTDLLADALKRCLAVSEVAGVRAVVTHAIDETAMAFYRRHGFLASPLGEKVLMM
PIETIRAVFADQ

Download         Length: 519 bp

Antitoxin


Download         Length: 56 a.a.        Molecular weight: 6279.16 Da        Isoelectric Point: 4.5899

>AT264200 WP_270183533.1 NZ_CP110774:3354077-3354244 [Acidocella sp. MX-AZ03]
MLDSARRQAEDTILDQRVFFLAPDAHEAFLAMLDAPAQDVAELRARLTKPPVWDR

Download         Length: 168 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References