Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1888523..1889148 Replicon chromosome
Accession NZ_CP110774
Organism Acidocella sp. MX-AZ03

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GT370_RS10520 Protein ID WP_008494675.1
Coordinates 1888523..1888924 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GT370_RS10525 Protein ID WP_039885345.1
Coordinates 1888924..1889148 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT370_RS10500 (GT370_10480) 1884229..1885017 + 789 WP_083878705.1 class I SAM-dependent methyltransferase -
GT370_RS10505 (GT370_10485) 1885353..1885718 + 366 WP_144052762.1 hypothetical protein -
GT370_RS10510 (GT370_10490) 1886027..1886677 + 651 WP_270183042.1 DUF4113 domain-containing protein -
GT370_RS10515 (GT370_10495) 1886820..1888166 - 1347 WP_008494677.1 site-specific integrase -
GT370_RS10520 (GT370_10500) 1888523..1888924 - 402 WP_008494675.1 tRNA(fMet)-specific endonuclease VapC Toxin
GT370_RS10525 (GT370_10505) 1888924..1889148 - 225 WP_039885345.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GT370_RS10530 (GT370_10510) 1889228..1890673 - 1446 WP_008494673.1 hypothetical protein -
GT370_RS10535 (GT370_10515) 1890834..1891610 + 777 WP_270183043.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-116)

Antitoxin

SpoVT-AbrB domain

(9-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14951.23 Da        Isoelectric Point: 7.7774

>T264199 WP_008494675.1 NZ_CP110774:c1888924-1888523 [Acidocella sp. MX-AZ03]
MLRYMLDTNLCIRVLRDRPQGVRARFNANAEALCLSDVVLYELLYGAERSNDPPRIRREVEHFAGRLTVLPFDSEAAAHT
AEICGDLKRRGNVIGPYDLMIAGHARSKGLIIVTGNLGEFQRVLGVRSEDWLV

Download         Length: 402 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8249.42 Da        Isoelectric Point: 5.0190

>AT264199 WP_039885345.1 NZ_CP110774:c1889148-1888924 [Acidocella sp. MX-AZ03]
MLARTSLFLSNRSQAVRLPKAVAFSEGVREVVIVPDGPRRIIAPAEAAWDDFFDAPGIDLGERVQPMAQEREHF

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References