Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1787472..1788325 Replicon chromosome
Accession NZ_CP110774
Organism Acidocella sp. MX-AZ03

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag GT370_RS10015 Protein ID WP_039885796.1
Coordinates 1787472..1787990 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID K5YGS5
Locus tag GT370_RS10020 Protein ID WP_008495825.1
Coordinates 1788032..1788325 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT370_RS09985 (GT370_09965) 1782484..1783533 + 1050 WP_039885813.1 IS5 family transposase -
GT370_RS09990 (GT370_09970) 1783860..1784225 - 366 WP_008495839.1 IS5/IS1182 family transposase -
GT370_RS09995 (GT370_09975) 1784314..1784751 - 438 WP_008495838.1 autoinducer binding domain-containing protein -
GT370_RS10000 (GT370_09980) 1785179..1785436 + 258 WP_270183519.1 hypothetical protein -
GT370_RS10005 (GT370_09985) 1785786..1786724 + 939 WP_039885801.1 hypothetical protein -
GT370_RS10010 (GT370_09990) 1786712..1787416 + 705 WP_270183534.1 hypothetical protein -
GT370_RS10015 (GT370_09995) 1787472..1787990 - 519 WP_039885796.1 GNAT family N-acetyltransferase Toxin
GT370_RS10020 (GT370_10000) 1788032..1788325 - 294 WP_008495825.1 DUF1778 domain-containing protein Antitoxin
GT370_RS10025 (GT370_10005) 1788473..1789264 + 792 WP_008495824.1 hypothetical protein -
GT370_RS10030 (GT370_10010) 1789433..1789876 + 444 WP_008495634.1 carboxymuconolactone decarboxylase family protein -
GT370_RS10035 (GT370_10015) 1789880..1790758 + 879 WP_008495635.1 RNA polymerase sigma factor SigJ -
GT370_RS10040 (GT370_10020) 1791046..1791369 + 324 WP_270184311.1 GNAT family N-acetyltransferase -
GT370_RS10045 (GT370_10025) 1791597..1792510 - 914 Protein_1972 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(57-148)

Antitoxin

Vibrio phage ICP1, Orf50

(16-87)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19049.16 Da        Isoelectric Point: 9.8224

>T264198 WP_039885796.1 NZ_CP110774:c1787990-1787472 [Acidocella sp. MX-AZ03]
VRRRLLPPERLTAAHDVSGFQNGRHPSLDEWLRDRALVSEGLSARTYVVRAGEPPHLVVGYYAITTAMEQRLSLPSAKLR
RGMPEQIPLMLIGRLAVDQRYHGIGLGTDLLADALKRCLAVSEVAGVRAVVTHAIDETAMAFYRRHGFLASPLGEKVLMM
PIETIRAVFADQ

Download         Length: 519 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10710.30 Da        Isoelectric Point: 7.0150

>AT264198 WP_008495825.1 NZ_CP110774:c1788325-1788032 [Acidocella sp. MX-AZ03]
MAQPAPAGPARKDDVIQIRASAETKAILTRAAALRGQKLSEFMLDSARRQAEDTILDQRVFFLAPDAHEAFLAMLDAPAQ
DVAELRARLTKPPVWDR

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB K5YGS5

References