264197

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1646298..1647700 Replicon chromosome
Accession NZ_CP110774
Organism Acidocella sp. MX-AZ03

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag GT370_RS09235 Protein ID WP_270184374.1
Coordinates 1647098..1647700 (-) Length 201 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag GT370_RS09230 Protein ID WP_270184264.1
Coordinates 1646298..1647098 (-) Length 267 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT370_RS09205 (GT370_09185) 1642103..1642549 - 447 Protein_1806 DEAD/DEAH box helicase family protein -
GT370_RS09210 (GT370_09190) 1642546..1643649 - 1104 WP_270184262.1 DUF4145 domain-containing protein -
GT370_RS09215 (GT370_09195) 1643745..1644320 + 576 WP_008492067.1 HD domain-containing protein -
GT370_RS09220 (GT370_09200) 1645039..1646013 - 975 WP_168118366.1 EcsC family protein -
GT370_RS09225 (GT370_09205) 1646036..1646218 - 183 WP_270184263.1 hypothetical protein -
GT370_RS09230 (GT370_09210) 1646298..1647098 - 801 WP_270184264.1 macro domain-containing protein Antitoxin
GT370_RS09235 (GT370_09215) 1647098..1647700 - 603 WP_270184374.1 DUF4433 domain-containing protein Toxin
GT370_RS09245 (GT370_09225) 1648098..1649213 - 1116 WP_008492062.1 TDT family transporter -
GT370_RS09250 (GT370_09230) 1649312..1650208 + 897 WP_008492061.1 LysR family transcriptional regulator -
GT370_RS09255 (GT370_09235) 1650198..1650530 - 333 WP_008492060.1 rhodanese-like domain-containing protein -
GT370_RS09260 (GT370_09240) 1650629..1651057 - 429 WP_008492059.1 cupin domain-containing protein -
GT370_RS09265 (GT370_09245) 1651124..1651681 + 558 WP_008492058.1 chromate transporter -
GT370_RS09270 (GT370_09250) 1651678..1652199 + 522 WP_008492057.1 chromate transporter -
GT370_RS09275 (GT370_09255) 1652404..1652529 + 126 WP_256378772.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-200)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 201 a.a.        Molecular weight: 21816.99 Da        Isoelectric Point: 7.1586

>T264197 WP_270184374.1 NZ_CP110774:c1647700-1647098 [Acidocella sp. MX-AZ03]
ITHIANLPWLLANGLHCANSAVVDPDFVAIGNPELIGKRTHRTVPLHPGGTLADYVPFYFTPKSPMLLNIKTGRGGIAQL
DNDKIVILVSSCQSMTQNGVTLLFTDRHAYVATAEWTTDQSRLGEIIDWDILRRHDFARDDSYLDKMERYQAEALAHRHV
PPGALLGVACASGSAKPIVEAAVAAAASAVKVFVRPGWYF

Download         Length: 603 bp

Antitoxin


Download         Length: 267 a.a.        Molecular weight: 29379.94 Da        Isoelectric Point: 10.0406

>AT264197 WP_270184264.1 NZ_CP110774:c1647098-1646298 [Acidocella sp. MX-AZ03]
MLRYTQGNLLESRAEALVNTVNTVGISGKGIALMFKEAYPDNFRAYEAACKAGQLEPGGLFITERHDMLGPRYIINFATK
QHWRNPSRLEWIEHGLAALGQEIEARGIRSIAIPPLGAGNGGLDWARVKHLIAESLAGHDCEIIVFEPTKTYQNVVKRNG
VEKLTPARAAMAEMIRRYEVLGFDCSMLEAQKLAWFLHRATQRLKLPVLIADDFTANRYGPTRIKSGICSIALMAATSPA
NGGWQTRARSIRSTSGMTVRIKSAPT

Download         Length: 801 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References