Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 70751..71376 Replicon chromosome
Accession NZ_CP110774
Organism Acidocella sp. MX-AZ03

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GT370_RS00410 Protein ID WP_008495786.1
Coordinates 70975..71376 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GT370_RS00405 Protein ID WP_039885769.1
Coordinates 70751..70975 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT370_RS00375 (GT370_00375) 66532..66675 - 144 WP_270183708.1 hypothetical protein -
GT370_RS00385 (GT370_00385) 67956..68285 + 330 WP_270183709.1 Gfo/Idh/MocA family oxidoreductase -
GT370_RS00390 (GT370_00390) 68282..68803 + 522 WP_270183710.1 Gfo/Idh/MocA family oxidoreductase -
GT370_RS00395 (GT370_00395) 69227..69781 + 555 WP_270183711.1 hypothetical protein -
GT370_RS00400 (GT370_00400) 69790..70671 + 882 WP_270183712.1 hypothetical protein -
GT370_RS00405 (GT370_00405) 70751..70975 + 225 WP_039885769.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GT370_RS00410 (GT370_00410) 70975..71376 + 402 WP_008495786.1 tRNA(fMet)-specific endonuclease VapC Toxin
GT370_RS00415 (GT370_00415) 71573..72265 - 693 WP_270183713.1 zinc ribbon domain-containing protein -
GT370_RS00420 (GT370_00420) 72796..73874 - 1079 Protein_77 IS5 family transposase -
GT370_RS00425 (GT370_00425) 74007..74324 - 318 WP_270183714.1 hypothetical protein -
GT370_RS00430 (GT370_00430) 74558..75297 + 740 Protein_79 IS5 family transposase -
GT370_RS00435 (GT370_00435) 75319..75762 - 444 WP_008495829.1 hypothetical protein -
GT370_RS00440 (GT370_00440) 75785..75913 - 129 WP_270183715.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-116)

Antitoxin

SpoVT-AbrB domain

(9-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15122.28 Da        Isoelectric Point: 5.6986

>T264196 WP_008495786.1 NZ_CP110774:70975-71376 [Acidocella sp. MX-AZ03]
MLRYMLDTNLCIRVLRDRPQEVRTRFNANAEALCLSDVVLYELLYGAERSNDPPRIRREVEHFAGRLTVLPFDSEAAAHT
AEIRGDLERLGNVIGPYDLMIAGHARSRGLIVVTGNLGEFQRVLGLRSEDWLE

Download         Length: 402 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8217.36 Da        Isoelectric Point: 5.0190

>AT264196 WP_039885769.1 NZ_CP110774:70751-70975 [Acidocella sp. MX-AZ03]
MLARTSLFLSNRSQAVRLPKAVAFSEGVHEVVIVPDGPRRIIAPAEAAWDDFFDAPGIDLGERVQPVAQERERF

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References