Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 213919..214592 Replicon chromosome
Accession NZ_CP110680
Organism Cellulomonas fimi strain Clb-11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OOT42_RS00980 Protein ID WP_273653110.1
Coordinates 213919..214353 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OOT42_RS00985 Protein ID WP_273653111.1
Coordinates 214350..214592 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOT42_RS00950 209046..210551 + 1506 WP_273653104.1 amino acid permease -
OOT42_RS00955 210619..211356 + 738 WP_273653105.1 MIP/aquaporin family protein -
OOT42_RS00960 211417..211857 - 441 WP_273653106.1 nitroreductase family deazaflavin-dependent oxidoreductase -
OOT42_RS00965 211933..212121 - 189 WP_273653107.1 antitoxin -
OOT42_RS00970 212286..212465 + 180 WP_273653108.1 DUF1918 domain-containing protein -
OOT42_RS00975 212506..213840 + 1335 WP_273653109.1 alpha/beta fold hydrolase -
OOT42_RS00980 213919..214353 - 435 WP_273653110.1 type II toxin-antitoxin system VapC family toxin Toxin
OOT42_RS00985 214350..214592 - 243 WP_273653111.1 ribbon-helix-helix protein, CopG family Antitoxin
OOT42_RS00990 214731..216266 - 1536 WP_273653112.1 HEAT repeat domain-containing protein -
OOT42_RS00995 216317..217243 - 927 WP_273654753.1 1,4-beta-xylanase -
OOT42_RS01000 217353..217781 - 429 WP_273653113.1 VOC family protein -
OOT42_RS01005 217839..218615 - 777 WP_273654754.1 uracil-DNA glycosylase -
OOT42_RS01010 218684..219223 - 540 WP_273653114.1 TIGR00725 family protein -
OOT42_RS01015 219368..219586 + 219 WP_273653115.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-133)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-40)


Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15522.66 Da        Isoelectric Point: 6.8442

>T264194 WP_273653110.1 NZ_CP110680:c214353-213919 [Cellulomonas fimi]
VILPDVNVLVGAARADAPQHARLRTWVEQHVPGPETFGLTDAVLGGVVRVLTHPRVFVRPSTLDEALGFVDALVAHPNVS
RVTPGPRHWQLVAELCRAADARGNLVADAQHAAVAIEHGATWVSQDRDFARFPGLRWVTAVEPG

Download         Length: 435 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8485.55 Da        Isoelectric Point: 4.5388

>AT264194 WP_273653111.1 NZ_CP110680:c214592-214350 [Cellulomonas fimi]
VRTTLLLPDDLYREVKSTAAASGETMTSFVEEALREALRRRARAGHAAVDFVVAPTGSGGLQPGVELDDSAALLDVMDAR

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References