Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT_toxin(toxin)
Location 3001278..3001767 Replicon chromosome
Accession NZ_CP110679
Organism Sphingomonas sp. S6-11

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OKW87_RS14415 Protein ID WP_265540557.1
Coordinates 3001278..3001538 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OKW87_RS14420 Protein ID WP_265540558.1
Coordinates 3001528..3001767 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKW87_RS14390 (OKW87_14390) 2997067..2998179 - 1113 WP_265540550.1 cell division protein ZapE -
OKW87_RS14395 (OKW87_14395) 2998176..2998628 - 453 WP_265540552.1 PaaI family thioesterase -
OKW87_RS14400 (OKW87_14400) 2998625..2999407 - 783 WP_265540554.1 succinate dehydrogenase iron-sulfur subunit -
OKW87_RS14405 (OKW87_14405) 2999516..3000124 - 609 WP_265540555.1 ATP-dependent Clp protease proteolytic subunit -
OKW87_RS14410 (OKW87_14410) 3000174..3001142 - 969 WP_265540556.1 C13 family peptidase -
OKW87_RS14415 (OKW87_14415) 3001278..3001538 + 261 WP_265540557.1 BrnT family toxin Toxin
OKW87_RS14420 (OKW87_14420) 3001528..3001767 + 240 WP_265540558.1 CopG family antitoxin Antitoxin
OKW87_RS14425 (OKW87_14425) 3001810..3003624 - 1815 WP_265540560.1 succinate dehydrogenase flavoprotein subunit -
OKW87_RS14430 (OKW87_14430) 3003624..3004013 - 390 WP_265540562.1 succinate dehydrogenase, hydrophobic membrane anchor protein -
OKW87_RS14435 (OKW87_14435) 3004006..3004428 - 423 WP_265540563.1 succinate dehydrogenase, cytochrome b556 subunit -
OKW87_RS14440 (OKW87_14440) 3004628..3005950 + 1323 WP_265544136.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(4-80)

Antitoxin

CopG antitoxin

(5-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9850.24 Da        Isoelectric Point: 8.7024

>T264193 WP_265540557.1 NZ_CP110679:3001278-3001538 [Sphingomonas sp. S6-11]
MFEFDPAKSAANLAKHGIDFEAARALWLDDRRQTPKSERPGEETRWLVIGMIQDVGWTAIVTHRGDRVPIISVRRARKEE
MALYGN

Download         Length: 261 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9319.56 Da        Isoelectric Point: 4.8950

>AT264193 WP_265540558.1 NZ_CP110679:3001528-3001767 [Sphingomonas sp. S6-11]
MEIEKISSEELDRRFDDGEEVLQYFDLSSARRPGLEVRRVNVDFPDWMIRNLDEHAKKRGVTRQALIKMWLADRLEAAG

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References