Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2892089..2892732 Replicon chromosome
Accession NZ_CP110678
Organism Sphingomonas sp. S1-29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OKW76_RS13755 Protein ID WP_265549422.1
Coordinates 2892089..2892481 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OKW76_RS13760 Protein ID WP_265549423.1
Coordinates 2892478..2892732 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKW76_RS13750 (OKW76_13750) 2887567..2892087 + 4521 WP_265552984.1 glutamate synthase large subunit -
OKW76_RS13755 (OKW76_13755) 2892089..2892481 - 393 WP_265549422.1 type II toxin-antitoxin system VapC family toxin Toxin
OKW76_RS13760 (OKW76_13760) 2892478..2892732 - 255 WP_265549423.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OKW76_RS13765 (OKW76_13765) 2892829..2893503 + 675 WP_265549424.1 glutathione S-transferase family protein -
OKW76_RS13770 (OKW76_13770) 2893518..2894144 + 627 WP_265549425.1 YbhB/YbcL family Raf kinase inhibitor-like protein -
OKW76_RS13775 (OKW76_13775) 2894154..2895005 - 852 WP_265549426.1 SDR family oxidoreductase -
OKW76_RS13780 (OKW76_13780) 2895416..2896465 - 1050 WP_265549427.1 GGDEF domain-containing protein -
OKW76_RS13785 (OKW76_13785) 2896589..2897125 - 537 WP_265549428.1 redoxin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Antitoxin VapB-like

(2-83)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13957.28 Da        Isoelectric Point: 6.0719

>T264191 WP_265549422.1 NZ_CP110678:c2892481-2892089 [Sphingomonas sp. S1-29]
VIAIDTSAILAIVLREPEAETFGALIQAHRRVFIGAPTLFELRMVTLGKFPEPVRAAVDALALAAPIETIAFTAEHHLVA
LDAFDRYGKGRHPASLNMGDCLSYAIAKIADCPLLFKGNDFGLTDIARVA

Download         Length: 393 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9362.61 Da        Isoelectric Point: 5.6210

>AT264191 WP_265549423.1 NZ_CP110678:c2892732-2892478 [Sphingomonas sp. S1-29]
VALSIKDEATDRMVRHYAKLKGLTYTSAIRVAVTDALRRENALPDEESFVERMRKVQDLVAAHPILDGRSADEIIGYDEH
GLPG

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References