Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2167956..2168424 Replicon chromosome
Accession NZ_CP110678
Organism Sphingomonas sp. S1-29

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag OKW76_RS10285 Protein ID WP_265548809.1
Coordinates 2168158..2168424 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag OKW76_RS10280 Protein ID WP_256505633.1
Coordinates 2167956..2168174 (+) Length 73 a.a.

Genomic Context

OKW76_RS10235OKW76_RS10245OKW76_RS10250OKW76_RS10255OKW76_RS10260OKW76_RS10270OKW76_RS10275OKW76_RS10280OKW76_RS10285OKW76_RS10290OKW76_RS10295OKW76_RS10300OKW76_RS10240OKW76_RS10265OKW76_RS10305OKW76_RS10310
Location: 2163858..2164583 (726 bp)
Type: Others
Protein ID: WP_265548801.1
Location: 2165004..2165588 (585 bp)
Type: Others
Protein ID: WP_265548803.1
Location: 2165591..2165875 (285 bp)
Type: Others
Protein ID: WP_256508112.1
Location: 2165872..2166171 (300 bp)
Type: Others
Protein ID: WP_265548804.1
Location: 2166237..2166362 (126 bp)
Type: Others
Protein ID: WP_265548805.1
Location: 2166673..2167221 (549 bp)
Type: Others
Protein ID: WP_265548807.1
Location: 2167471..2167899 (429 bp)
Type: Others
Protein ID: WP_265548808.1
Location: 2167956..2168174 (219 bp)
Type: Antitoxin
Protein ID: WP_256505633.1
Location: 2168158..2168424 (267 bp)
Type: Toxin
Protein ID: WP_265548809.1
Location: 2168497..2168769 (273 bp)
Type: Others
Protein ID: WP_265548810.1
Location: 2168766..2169032 (267 bp)
Type: Others
Protein ID: WP_265548811.1
Location: 2169108..2170037 (930 bp)
Type: Others
Protein ID: WP_265548812.1
Location: 2164584..2164955 (372 bp)
Type: Others
Protein ID: WP_265548802.1
Location: 2166410..2166616 (207 bp)
Type: Others
Protein ID: WP_265548806.1
Location: 2170184..2172124 (1941 bp)
Type: Others
Protein ID: WP_265548813.1
Location: 2172277..2172621 (345 bp)
Type: Others
Protein ID: WP_265548814.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OKW76_RS10235 (OKW76_10235)2163858..2164583+726WP_265548801.1bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG-
OKW76_RS10240 (OKW76_10240)2164584..2164955-372WP_265548802.1tRNA-binding protein-
OKW76_RS10245 (OKW76_10245)2165004..2165588+585WP_265548803.1hypothetical protein-
OKW76_RS10250 (OKW76_10250)2165591..2165875+285WP_256508112.1DUF427 domain-containing protein-
OKW76_RS10255 (OKW76_10255)2165872..2166171+300WP_265548804.1alkylphosphonate utilization protein-
OKW76_RS10260 (OKW76_10260)2166237..2166362+126WP_265548805.1hypothetical protein-
OKW76_RS10265 (OKW76_10265)2166410..2166616-207WP_265548806.1hypothetical protein-
OKW76_RS10270 (OKW76_10270)2166673..2167221+549WP_265548807.1hypothetical protein-
OKW76_RS10275 (OKW76_10275)2167471..2167899+429WP_265548808.1cupin domain-containing protein-
OKW76_RS10280 (OKW76_10280)2167956..2168174+219WP_256505633.1TraY domain-containing proteinAntitoxin
OKW76_RS10285 (OKW76_10285)2168158..2168424+267WP_265548809.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OKW76_RS10290 (OKW76_10290)2168497..2168769+273WP_265548810.1type II toxin-antitoxin system prevent-host-death family antitoxin-
OKW76_RS10295 (OKW76_10295)2168766..2169032+267WP_265548811.1Txe/YoeB family addiction module toxin-
OKW76_RS10300 (OKW76_10300)2169108..2170037+930WP_265548812.15'-nucleotidase-
OKW76_RS10305 (OKW76_10305)2170184..2172124-1941WP_265548813.1phosphomethylpyrimidine synthase ThiC-
OKW76_RS10310 (OKW76_10310)2172277..2172621-345WP_265548814.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10242.84 Da        Isoelectric Point: 10.4120

>T264188 WP_265548809.1 NZ_CP110678:2168158-2168424 [Sphingomonas sp. S1-29]
MAWRIEFLPEAAKELAKLDRTAAARIIKTLETRIAVQDDPRSLGSALTGDHAGYWRWRIGDYRVVARIEDDRVLILVVRV
AHRREVYR

Download         Length: 267 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8108.13 Da        Isoelectric Point: 4.3525

>AT264188 WP_256505633.1 NZ_CP110678:2167956-2168174 [Sphingomonas sp. S1-29]
MLAVRLDTETEARLEALAARTGRTKTFYAREAIVAHLDDLEDFYLAEERLRDFRDGDAIPLADLKAQLGLAD

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References