Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 3204759..3205304 Replicon chromosome
Accession NZ_CP110670
Organism Vibrio alginolyticus strain AUSMDU00064140

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OPR71_RS14685 Protein ID WP_140311992.1
Coordinates 3204759..3205055 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OPR71_RS14690 Protein ID WP_064377013.1
Coordinates 3205062..3205304 (-) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPR71_RS14665 (OPR71_14665) 3201678..3202739 + 1062 WP_064377016.1 LacI family DNA-binding transcriptional regulator -
OPR71_RS14670 (OPR71_14670) 3204021..3204278 + 258 WP_039989820.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OPR71_RS14675 (OPR71_14675) 3204266..3204568 + 303 WP_064377015.1 type II toxin-antitoxin system RelE/ParE family toxin -
OPR71_RS14680 (OPR71_14680) 3204604..3204696 + 93 WP_081107514.1 DUF3265 domain-containing protein -
OPR71_RS14685 (OPR71_14685) 3204759..3205055 - 297 WP_140311992.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OPR71_RS14690 (OPR71_14690) 3205062..3205304 - 243 WP_064377013.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OPR71_RS14695 (OPR71_14695) 3205417..3205509 + 93 WP_201785722.1 DUF3265 domain-containing protein -
OPR71_RS14700 (OPR71_14700) 3205544..3205939 + 396 WP_053306558.1 DUF3465 domain-containing protein -
OPR71_RS14705 (OPR71_14705) 3206090..3206548 + 459 WP_213889230.1 GNAT family N-acetyltransferase -
OPR71_RS14710 (OPR71_14710) 3206582..3207538 - 957 WP_033906599.1 IS110 family transposase -
OPR71_RS14715 (OPR71_14715) 3207759..3207851 + 93 WP_197649978.1 DUF3265 domain-containing protein -
OPR71_RS14720 (OPR71_14720) 3207884..3208420 + 537 WP_267922936.1 DUF1643 domain-containing protein -
OPR71_RS14725 (OPR71_14725) 3208488..3209638 + 1151 WP_267922937.1 IS3 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - ugd / rfaD / wbtL 2962347..3216016 253669


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11280.01 Da        Isoelectric Point: 10.0001

>T264124 WP_140311992.1 NZ_CP110670:c3205055-3204759 [Vibrio alginolyticus]
MQKNKYKLSKLAQTHLRKIKSYTVKNFSEMQWRSYKDTLLTGFQMLADNPAVGRSCDDIYPSGFYFPVGKHTAYFTKEDG
FILVVAVLGQSQLPQNHL

Download         Length: 297 bp


Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9019.20 Da        Isoelectric Point: 4.6135

>AT264124 WP_064377013.1 NZ_CP110670:c3205304-3205062 [Vibrio alginolyticus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKTDYLKHCFESAKQDLTQGDVIDGEDFLNAL

Download         Length: 243 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References