Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3655941..3656719 Replicon chromosome
Accession NC_017271
Organism Xanthomonas campestris pv. raphani 756C

Toxin (Protein)


Gene name TacT2 Uniprot ID G0CD68
Locus tag XCR_RS15605 Protein ID WP_014508713.1
Coordinates 3656228..3656719 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID G0CD67
Locus tag XCR_RS15600 Protein ID WP_014508712.1
Coordinates 3655941..3656231 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCR_RS15575 3651388..3651819 - 432 WP_043922199.1 pilin -
XCR_RS15580 3652168..3653425 + 1258 Protein_3087 type II secretion system F family protein -
XCR_RS15585 3653432..3654295 + 864 WP_011038216.1 A24 family peptidase -
XCR_RS15590 3654309..3654932 + 624 WP_014508710.1 dephospho-CoA kinase -
XCR_RS15595 3655465..3655866 + 402 WP_043921912.1 type I toxin-antitoxin system SymE family toxin -
XCR_RS15600 3655941..3656231 + 291 WP_014508712.1 DUF1778 domain-containing protein Antitoxin
XCR_RS15605 3656228..3656719 + 492 WP_014508713.1 GNAT family N-acetyltransferase Toxin
XCR_RS15610 3656862..3658196 - 1335 WP_012437598.1 HAMP domain-containing histidine kinase -
XCR_RS15615 3658189..3658866 - 678 WP_003490678.1 response regulator transcription factor -
XCR_RS15620 3659516..3660391 - 876 WP_043921913.1 30S ribosomal protein S6--L-glutamate ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - pilC 3641705..3700042 58337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17492.14 Da        Isoelectric Point: 8.9765

>T26411 WP_014508713.1 NC_017271:3656228-3656719 [Xanthomonas campestris pv. raphani 756C]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACADDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGKGFGRALVQDAGKRVLHAADTVGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

>T26411 NC_017271:3656228-3656719 [Xanthomonas campestris pv. raphani 756C]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGAACCTTCGTTGCCTGCGCGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTCGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGCAGGCTTGCTGTTGACCAATCCCTGCACGGCAAAGGGTTTGGTCGCGCCCTGGTGCAGGA
TGCAGGCAAGCGCGTCCTGCATGCAGCCGACACCGTTGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10648.20 Da        Isoelectric Point: 10.5480

>AT26411 WP_014508712.1 NC_017271:3655941-3656231 [Xanthomonas campestris pv. raphani 756C]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp

>AT26411 NC_017271:3655941-3656231 [Xanthomonas campestris pv. raphani 756C]
ATGTCCACACCCAACACTACGCCCGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCGCGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G0CD68

Antitoxin

Source ID Structure
AlphaFold DB A0A3E1LB51

References